102234-40-2Relevant academic research and scientific papers
Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer’s disease agents
Yun, Yinling,Miao, Yuhang,Sun, Xiaoya,Sun, Jie,Wang, Xiaojing
, p. 1346 - 1356 (2021)
Alzheimer's disease (AD) is a type of progressive dementia caused by degeneration of the nervous system. A single target drug usually does not work well. Therefore, multi-target drugs are designed and developed so that one drug can specifically bind to mu
Synthesis and biological evaluation of 3-functionalized 2-phenyl- and 2-alkylbenzo[b]furans as antiproliferative agents against human melanoma cell line
Kwiecień, Halina,Peru?yńska, Magdalena,Stachowicz, Karolina,Piotrowska, Katarzyna,Bujak, Joanna,Kopytko, Patrycja,Dro?dzik, Marek
, (2019/04/29)
The key function of microtubules and mitotic spindle in cell division make them attractive targets in anticancer therapy. In the present study, functionalized in 3 position 2-phenyl- and 2-alkylbenzo[b]furans were synthesized and evaluated as antitumor ag
Intramolecular Cycloaddition Reactions of Ketene and Carbonyl Groups. A New Synthesis of Benzofurans
Brady, William T.,Giang, Frank Y.
, p. 2145 - 2147 (2007/10/02)
(o-Carbonylphenoxy)acetyl chlorides are dehydrochlorinated to the corresponding (o-carbonylphenoxy)ketenes which undergo a cycloaddition reaction to yield tricyclic β-lactones which spontaneously decarboxylate to benzofurans.
