4265-21-8Relevant articles and documents
Iminyl-radicals by electrochemical decarboxylation of α-imino-oxy acids: construction of indole-fused polycyclics
Wan, Jin-Lin,Cui, Jian-Feng,Zhong, Wei-Qiang,Huang, Jing-Mei
supporting information, p. 10242 - 10245 (2021/10/12)
Iminyl radicals are reactive intermediates that can be used for the construction of various valuable heterocycles. Herein, the electrochemical decarboxylation of α-imino-oxy acids for the generation of iminyl radicals has been accomplished under exogenous-oxidant- and metal-free conditions through the use ofnBu4NBr as a mediator. The resulting iminyl radicals undergo intramolecular cyclization smoothly with the adjacent (hetero)arenes to afford a series of indole-fused polycyclic compounds.
Synthesis and biological evaluation of 3-functionalized 2-phenyl- and 2-alkylbenzo[b]furans as antiproliferative agents against human melanoma cell line
Kwiecień, Halina,Peru?yńska, Magdalena,Stachowicz, Karolina,Piotrowska, Katarzyna,Bujak, Joanna,Kopytko, Patrycja,Dro?dzik, Marek
, (2019/04/29)
The key function of microtubules and mitotic spindle in cell division make them attractive targets in anticancer therapy. In the present study, functionalized in 3 position 2-phenyl- and 2-alkylbenzo[b]furans were synthesized and evaluated as antitumor ag
CONDENSED FURAN DERIVATIVES AS ADENOSINE ANTAGONISTS
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Page 30-31, (2010/02/09)
A novel compound of the following formula (I): wherein Z is a phenyl or pyridyl which condenses to a furan ring; X is CH or N; R1 is hydrogen or optionally substituted lower alkyl; R2 is hydrogen, halogen or lower alkoxy; and R3
