102302-75-0

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 123-11-5 4-methoxy-benzaldehyde 
• 82319-42-4 (S)-N-(4-methoxybenzylidene)-α-methylbenzylamine 

Downstream Products

• 102341-89-9 (3aS,6aR)-1-((S)-1-Phenyl-ethyl)-tetrahydro-furo[3,2-c]isoxazol-5-one 
• 102302-81-8 (3aR,6aS)-1-((S)-1-Phenyl-ethyl)-tetrahydro-furo[3,2-c]isoxazol-5-one 
• 78853-92-6 (3R,3aS,6aR)-3-Methyl-1-((S)-1-phenyl-ethyl)-tetrahydro-furo[3,2-c]isoxazol-5-one 
• 102341-87-7 (3R,3aR,6aS)-3-Methyl-1-((S)-1-phenyl-ethyl)-tetrahydro-furo[3,2-c]isoxazol-5-one 
• 102302-84-1 (3aR,6aS)-3,3-Dimethyl-1-((S)-1-phenyl-ethyl)-tetrahydro-furo[3,2-c]isoxazol-5-one 
• 102341-91-3 (3aS,6aR)-3,3-Dimethyl-1-((S)-1-phenyl-ethyl)-tetrahydro-furo[3,2-c]isoxazol-5-one 
• 78798-33-1 (S)-N-hydroxy-α-methyl-benzenemethanamine ethanedioate 

Relevant academic research and scientific papers

Enantio-and diastereoselective oxidation of N-alkylimines using chiral-bromonitriles and hydrogen peroxide system

Chiral-bromonitriles were prepared with good chemical and optical yields starting from natural-amino acids by dehydrating the corresponding α-bromoamides with thionyl chloride. The combined system-bromonitriles/ hydrogen peroxide was examined for the enantio-and diastereoselective oxidation of N-alkylimines in basic media at room temperature. The oxidation of N-tertiobutylarylimines leads to optically active oxaziridines with moderate enantiomeric excess. However, the oxidation of (S)-1-phenylethylarylimines affords the corresponding oxaziridines with good diasteromeric excess up to 97/3 as proved by gaseous-phase chromatography.