10235-65-1

Usage

Uses

Used in Pharmaceutical Industry:
4,6-Dichloro-2-(2-pyridinyl)pyrimidine is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of diverse compounds with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-Dichloro-2-(2-pyridinyl)pyrimidine is employed as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used as a Research Reagent:
4,6-Dichloro-2-(2-pyridinyl)pyrimidine is used as a research reagent in organic synthesis and chemical analysis. Its presence in various chemical reactions aids scientists in understanding the mechanisms and outcomes of these processes, ultimately contributing to the advancement of chemical knowledge and innovation.

InChI:InChI=1/C9H5Cl2N3/c10-7-5-8(11)14-9(13-7)6-3-1-2-4-12-6/h1-5H

Upstream product

• 52313-50-5 pyridine-2-carboxamidine 
• 100-70-9 2-Cyanopyridine 
• 10198-74-0 2-pyridin-2-yl-1H-pyrimidine-4,6-dione 

Downstream Products

• 1014720-73-0 6-chloro-2-(2-pyridin-2-yl)pyrimidin-4-ylamine 
• 1373423-17-6 ethyl N-[6-chloro-2-(2-pyridinyl)-4-pyrimidinyl]-β-alaninate 
• 1373422-53-7 GSK-J1 
• 1373421-99-8 N-[6-[(phenylmethyl)amino]-2-(2-pyridinyl)-4-pyrimidinyl]-β-alanine 
• 1373423-53-0 GSKJ4 
• 1373423-54-1 Ethyl N-[6-[(phenylmethyl)amino]-2-(2-pyridinyl)-4-pyrimidinyl]-β-alaninate 
• 67-63-0 isopropyl alcohol 
• 1373423-88-1 ethyl N-[6-({2-[3-(β-alanylamino)phenyl]ethyl}amino)-2-(2-pyridinyl)-4-pyrimidinyl]-β-alaninate 
• 1373423-87-0 ethyl N-[6-[(2-{3-[(N-{[(1,1-dimethylethyl)oxy]carbonyl}-β-alanyl)amino]phenyl}ethyl)amino]-2-(2-pyridinyl)-4-pyrimidinyl]-β-alaninate 
• 1373423-86-9 ethyl N-[6-{[2-(3-aminophenyl)ethyl]amino}-2-(2-pyridinyl)-4-pyrimidinyl]-β-alaninate 
• 1172113-85-7 {4-[5-(6-chloro-2-pyridin-2-yl-pyrimidin-4-yl)-pyridin-3-yl]-phenyl}-(4-isopropyl-piperazin-1-yl)-methanone 
• 1172113-88-0 4-chloro-6-[5-(3-methoxy-phenyl)-pyridin-3-yl]-2-pyridin-2-yl-pyrimidine 

Relevant academic research and scientific papers

Histone demethylase JMJD3 inhibitor, preparation method and application thereof

The invention relates to compound shown as general formula (I), its stereoisomer, pharmaceutically acceptable salt, prodrug, solvate, hydrate, ester and crystal. The compound shown as general formula (I) in the invention can inhibit histone demethylase JMJD3, is used for regulating the apparent states of cells and treating a series of histone demethylase JMJD3 mediated diseases and symptoms, which specifically include lung cancer, liver cancer, primary hodgkin lymphoma, some hematologic malignant tumors, inflammation and self-immune diseases, etc.

Novel Pyrimidine- And Triazine-Hepcidine Antagonists

The present invention relates to new hepcidin antagonists, pharmaceutical compositions containing them and the use thereof as a drug, in particular for the treatment of iron metabolism disorders such as, in particular, iron deficiency diseases and anaemia, in particular anaemia associated with chronic inflammatory disease (ACD: anaemia of chronic disease and AI: anaemia of inflammation).

PYRIMIDINES AS KINASE INHIBITORS

Compounds of formula (I) in free or salt or solvate form, where T1, T2, and T3 have the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmo

Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: wherein Z1, Z2, R1, R2, R3, R4, R5and R6are defined herein. These compounds are useful as anti-coagulants.

Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: wherein Z1, Z2, R1, R2, R3, R4, R5 and R6 are defined herein. These compounds are useful as anti-coagulants.