102450-77-1Relevant academic research and scientific papers
Synthesis of selectively mono-N-arylated aliphatic diamines via iridium-catalyzed amine alkylation
Blank, Benoit,Michlik, Stefan,Kempe, Rhett
experimental part, p. 2903 - 2911 (2010/03/25)
A highly selective phosphorus/nitrogen (P,N) ligand-based iridium catalyst system efficiently catalyzes the reaction of arylamines with unprotected amino alcohols, yielding N-arylated aliphatic diamines in yields of up to 93%. The reaction can be performe
RENIN INHIBITORS
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Page/Page column 106, (2009/01/23)
The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagon
