1024602-85-4

Usage

Molecular structure

2-(2-oxo-2-(4-(3-oxo-3-(2-oxoazetidin-1-yl)propyl)phenylamino)ethoxy)acetic acid is a complex organic compound with multiple functional groups and a cyclic azetidine ring.

Functional groups

The compound contains carbonyl (2), phenyl, amino, ethoxy, and acetic acid moieties, which contribute to its chemical reactivity and potential applications.

Cyclic azetidine ring

The presence of a 2-oxoazetidine ring suggests that the compound may have unique chemical and physical properties, as well as potential applications in various fields.

Classification

As an organic acid, the compound is part of a large class of compounds with a wide range of applications in pharmaceuticals, materials science, and other industries.

Potential applications

Although specific biological and chemical properties are not mentioned, the presence of multiple functional groups suggests that the compound may have various interactions and potential applications in pharmaceuticals, materials science, or other fields.

Complexity

The long chemical name and complex structure of the compound may pose challenges in synthesis, purification, and characterization, requiring advanced techniques and expertise.

Upstream product

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• 1024869-25-7 C₁₂H₁₄N₂O₂ 
• 16642-79-8 3-(4-nitrophenyl)propionic acid 
• 107324-93-6 3-(p-nitrophenyl)propanoyl chloride 
• 1024602-82-1 1-(3-(4-nitrophenyl)propanoyl)azetidin-2-one 
• 1024602-84-3 1-(3-(4-aminophenyl)propanoyl)azetidin-2-one hydrochloride 

Downstream Products

• 1415920-62-5 2-(2-oxo-2-(4-(3-oxo-3-(2-oxoazetidin-1-yl)propyl)phenylamino)ethoxy)acetate pentafluorophenol ester 
• 1531639-48-1 C₁₆H₁₆N₂O₅ 
• 1196075-64-5 C₂₀H₂₁N₃O₈ 
• 1445318-02-4 4-nitrophenyl 2-(2-oxo-2-((4-(3-oxo-3-(2-oxoazetidin-1-yl)propyl)phenyl)amino)ethoxy)acetate 

Relevant academic research and scientific papers

PROCESSES FOR PREPARING PEPTIDE CONJUGATES AND LINKERS

The present invention provides a process for preparing a compound of Formula 5b, as well as intermediates thereof, and novel classes of compounds useful in process for preparing these and similar compounds.

Chromatography- and lyophilization-free synthesis of a peptide- linker conjugate

An optimized and scalable process to manufacture peptide-linker conjugate 1 is reported that avoids the chromatographic purification and lyophilization that are typically required for the isolation of this type of compound. An operationally simple protoco

Development of a long acting human growth hormone analog suitable for once a week dosing

Human growth hormone was conjugated to a carrier aldolase antibody, using a novel linker by connecting a disulphide bond in growth hormone to a lysine-94 amine located on the Fab arm of the antibody. The resulting CovX body showed reduced affinity towards human growth hormone receptor, reduced cell-based activity, but improved pharmacodynamic properties. We have demonstrated that this CovX-body, given once a week, showed comparable activity as growth hormone given daily in an in vivo hypophysectomized rat model.