1024606-02-7Relevant academic research and scientific papers
Discovery of novel SCD1 inhibitors: 5-Alkyl-4,5-dihydro-3H-spiro[1,5- benzoxazepine-2,4′-piperidine] analogs
Uto, Yoshikazu,Ueno, Yuko,Kiyotsuka, Yohei,Miyazawa, Yuriko,Kurata, Hitoshi,Ogata, Tsuneaki,Takagi, Toshiyuki,Wakimoto, Satoko,Ohsumi, Jun
, p. 1892 - 1896 (2011/04/27)
Expansion of the 6-membered ring and subsequent fine-tuning of the newly obtained 7-membered spiropiperidine structure resulted in the discovery of a series of novel and potent SCD1 inhibitors. Preliminary SAR was explored by modifying an alkyl chain on t
