1024616-73-6

Basic information

• Product Name: 1-methyl-5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine
• Synonyms: 1-methyl-5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine
• CAS NO: 1024616-73-6
• Molecular Weight: 536.7
• Mol File: 1024616-73-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine(1024616-73-6)
• EPA Substance Registry System: 1-methyl-5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine(1024616-73-6)

Safety Data

• Hazardous Substances Data: 1024616-73-6(Hazardous Substances Data)

Upstream product

• 1024616-70-3 5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine 
• 74-88-4 methyl iodide 

Downstream Products

• 13860-38-3 N¹-methylpseudouridine 
• 1024616-83-8 1-methyl-3-[4-O-(tert-butyldimethylsilyl)butyl]-5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine 
• 1024616-77-0 1-methyl-3-[(S)-3-N-(tert-butoxycarbonyl)amino-3-methoxycarbonylpropyl]-5'-O-(tert-butyldiphenylsilyl)-2',3'-O-(isopropylidene)pseudouridine 

Relevant articles and documents

Synthesis and solution conformation studies of 3-substituted uridine and pseudouridine derivatives

A series of 3-substituted uridine and pseudouridine derivatives, based on the naturally occurring 3-(3-amino-3-carboxypropyl) modification, were synthesized. Their aqueous solution conformations were determined by using circular dichroism and NMR spectroscopy. Functional group composition and chain length were shown to have only a subtle influence on the distribution of syn/anti conformations of the modified nucleosides. The dominating factor appears to be the glycosidic linkage (C- vs. N-glycoside) in determining the nucleoside conformation.