1024656-00-5

Upstream product

• 106-39-8 bromochlorobenzene 
• 1339958-80-3 2-benzyl-4-phenyl-2H-1,2,3-triazole 
• 100-39-0 benzyl bromide 
• 120106-67-4 4-(4-chlorophenyl)-5-phenyl-1H(2H)-[1,2,3]triazole 

Relevant academic research and scientific papers

Palladium-Catalyzed Direct Diarylation of 2-Benzyl-1,2,3-triazole: a Simple Access to 4-Aryl- or 4,5-Diaryl-2-benzyl-1,2,3-triazoles and Phenanthro[9,10-d][1,2,3]triazoles

The reactivity of 2-benzyl-1,2,3-triazole in palladium-catalyzed direct arylation was studied. The reaction conditions for the selective synthesis of 2-benzyl-4-aryl-1,2,3-triazoles in moderate to high yields using phosphine-free Pd(OAc)2 catalyst and inexpensive KOAc base have been found. Then, from these 4-aryl-1,2,3-triazoles, the palladium-catalyzed C?H bond functionalization of the C5-position allowed the synthesis of the corresponding 4,5-diarylated 2-benzyl-1,2,3-triazoles. This selective 4,5-diarylation of 2-benzyl-1,2,3-triazole was successfully applied for the straightforward building of the π-extended polycyclic heteroaromatic structures phenanthro[9,10-d][1,2,3]triazoles through Pd-catalyzed C4- and C5-intermolecular arylations followed by Pd-catalyzed C?H intramolecular arylation.

N-substituted-1,2,3-triazoles: Synthesis, characterization and evaluation as cannabinoid ligands

A series of new N1-, N2-and N3-substituted 1,2,3-triazole derivatives has been synthesized by cycloaddition of butyltin azide with substituted alkynes followed by a N-alkylation reaction. The regioisomers have been isolated and characterized using NMR tec

1,2,3-Triazole derivatives as cannabinoid-receptor modulators

The invention relates to the use of compounds having pharmacological activity towards the so-called cannabonid receptors, and more particularly to some 1,2,3-triazole derivatives of formula (I): to processes of preparation of such compounds and to pharmac