102477-88-3

Upstream product

• 61714-10-1 1,1-Diphenyl-3-<2-hydroxy-phenyl>-prop-2-en-1-ol 
• 343309-52-4 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol 
• 533-58-4 2-Iodophenol 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 
• 184368-89-6 1-iodo-2-(tert-butyldimethylsilyloxy)benzene 

Relevant academic research and scientific papers

Hydroxyl Assisted, Photoredox/Cobalt Co-catalyzed Semi-Hydrogenation and Tandem Cyclization of o-Alkynylphenols for Access to 2,3-Dihydrobenzofurans

Herein, a hydroxyl assisted, photoredox/cobalt co-catalyzed semi-hydrogenation and tandem cyclization of o-alkynylphenols is developed towards direct assembly of 2,3-dihydrobenzofurans. Moderate to good yields were obtained for a range of sterically and electronically diverse 2-propynolphenols under mild conditions. Mechanistic studies demonstrated the inevitable role of the alcoholic hydroxyl group with (Z)-alkene as the real intermediate. Finally, a key low-valent cobalt catalyzed intramolecular hydroetherification of alkene is proposed. (Figure presented.).