61714-10-1

Basic information

• Product Name: Benzenemethanol, a-[2-(2-hydroxyphenyl)ethenyl]-a-phenyl-, (Z)-
• CAS NO: 61714-10-1
• Molecular Formula: C21H18O2
• Molecular Weight: 302.373
• Mol File: 61714-10-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-[2-(2-hydroxyphenyl)ethenyl]-a-phenyl-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-[2-(2-hydroxyphenyl)ethenyl]-a-phenyl-, (Z)-(61714-10-1)
• EPA Substance Registry System: Benzenemethanol, a-[2-(2-hydroxyphenyl)ethenyl]-a-phenyl-, (Z)-(61714-10-1)

Safety Data

• Hazardous Substances Data: 61714-10-1(Hazardous Substances Data)

Upstream product

• 343309-52-4 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol 
• 92-45-5 3-chloro-2H-chromen-2-one 

Downstream Products

• 102477-88-3 (2,3-dihydrobenzofuran-2-yl)diphenylmethanol 

Relevant articles and documents

Hydroxyl Assisted, Photoredox/Cobalt Co-catalyzed Semi-Hydrogenation and Tandem Cyclization of o-Alkynylphenols for Access to 2,3-Dihydrobenzofurans

Herein, a hydroxyl assisted, photoredox/cobalt co-catalyzed semi-hydrogenation and tandem cyclization of o-alkynylphenols is developed towards direct assembly of 2,3-dihydrobenzofurans. Moderate to good yields were obtained for a range of sterically and electronically diverse 2-propynolphenols under mild conditions. Mechanistic studies demonstrated the inevitable role of the alcoholic hydroxyl group with (Z)-alkene as the real intermediate. Finally, a key low-valent cobalt catalyzed intramolecular hydroetherification of alkene is proposed. (Figure presented.).

Reaction of 3-Halogeno-2H-1-benzopyran-2-ones with Organometallic Compounds. Synthesis of 4-Alkyl-2H-1-benzopyran-2-ones. X-Ray Molecular Structure of 3-Bromo-3,4-dihydro-4-isopropylcoumarin

3-Halogeno-2H-1-benzopyran-2-ones react with magnesium, lithium, aluminium and copper derivatives to give 3,4-dihydrocuomarins and 3-(o-hydroxyphenyl)propenols as major products.The nature and the ratio of the products in the final mixture depend on the solvent and on the organometallic reagent.Grignard derivatives yield 1,4-monoalkylation compounds in tetrahydrofuran (THF) or 1,2-dialkylation derivatives in toluene.In some cases the dehalogenation competes with the 1,2-alkylation process in the reactions with alkyllithiums.The presence of the halogen at C-3 increases the reductive ability of organoaluminiums.In general, the reaction with lithium dialkylcuprates leads to complex mixtures of products.The 4-alkyl-3-halogeno-3,4-dihydrocuomarins obtained undergo dehydrohalogenation easily, and lead to 4-alkylcuomarins in good yields.The tandem alkylation-dehydrohalogenation of 3-halogeno-2H-1-benzopyran-2-ones constitutes a versatile synthesis of 4-alkylcuomarins.