1025014-18-9Relevant academic research and scientific papers
Silver-Catalyzed Coupling of Two Csp3-H Groups and One-Pot Synthesis of Tetrasubstituted Furans, Thiophenes, and Pyrroles
Mao, Shuai,Zhu, Xue-Qing,Gao, Ya-Ru,Guo, Dong-Dong,Wang, Yong-Qiang
, p. 11335 - 11339 (2015/08/03)
Silver-catalyzed coupling of two Csp3-H groups to form 1,4-diketones have been developed for the first time. The resultant ketones then undergo cyclization to synthesize tetrasubstituted furans, thiophenes, and pyrroles from benzyl ketone derivatives in a one-pot reaction process. This highly-efficient synthetic method, which utilizes air as the terminal oxidant and readily accessible starting materials, displays a wide substrate scope and broad functional-group tolerance.
Selective mono- to perarylations of tetrabromothiophene by a cyclobutene-1,2-diylbisimidazolium preligand
Rahimi, Alireza,Namyslo, Jan C.,Drafz, Martin H. H.,Halm, Julian,Huebner, Eike,Nieger, Martin,Rautzenberg, Nicola,Schmidt, Andreas
, p. 7316 - 7325 (2011/11/05)
(Cyclobut-1-ene-1,2-diyl)bis(1-methylimidazolium)tetrafluoroborate is applied as preligand in palladium-catalyzed cross-coupling reactions starting from tetrabromothiophene for the synthesis of mono-, bi-, tri-, and tetraaryl-substituted thiophenes bearin
Palladium-catalyzed perarylation of 3-thiophene- and 3-furancarboxylic acids accompanied by C-H bond cleavage and decarboxylation
Nakano, Masaya,Tsurugi, Hayato,Satoh, Tetsuya,Miura, Masahiro
supporting information; experimental part, p. 1851 - 1854 (2009/04/10)
3-Thiophene- and 3-furancarboxylic acids efficiently undergo perarylation accompanied by cleavage of the three C-H bonds and decarboxylation upon treatment with excess aryl bromides in the presence of a palladium catalyst to give the corresponding tetraarylated products in good yields.
