102552-76-1

Basic information

• Product Name: 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester
• CAS NO: 102552-76-1
• Molecular Formula: C20H24 N2 O2
• Molecular Weight: 324.423
• Mol File: 102552-76-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester(102552-76-1)
• EPA Substance Registry System: 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester(102552-76-1)

Safety Data

• Hazardous Substances Data: 102552-76-1(Hazardous Substances Data)

Upstream product

• 120-43-4 4-ethoxycarbonylpiperazine 
• 90-99-3 diphenylchloromethane 

Downstream Products

• 85063-77-0 4-benzhydryl-piperazine-1-carbonimidic acid amide; sulfate 
• 87887-84-1 1-benzhydryl-4-(2-dimethylamino-ethyl)-piperazine 
• 101785-02-8 (4-Benzhydryl-piperazino)-methanol 
• 121943-14-4 1-benzhydryl-4-(8-(methylthio)-10,11-dihydrodibenzothiepin-10-yl)piperazine 
• 121943-12-2 1-benzhydryl-4-(8-chloro-10,11-dihydrodibenzothiepin-10-yl)piperazine 
• 121943-07-5 1-benzhydryl-4-(10,11-dihydrodibenzothiepin-10-yl)piperazine 
• 60607-34-3 oxatomide 
• 58103-08-5 ethyl 2-(4-benzylhydrylpiperazin-1-yl)acetate 
• 139329-22-9 5-(4-benzhydryl-piperazin-1-yl)-pentanoic acid ethyl ester 
• 788126-77-2 6-(4-Benzhydryl-piperazin-1-yl)-hexanoic acid methyl ester 
• 113561-11-8 3-(4-Benzhydryl-piperazin-1-yl)-propionic acid ethyl ester 
• 139359-42-5 4-(4-Benzhydryl-piperazin-1-yl)-butyric acid ethyl ester 
• 157665-24-2 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acid 
• 82-92-8 N-benzhydryl-N'-methylpiperazine 

Relevant articles and documents

Hybrid approach for the design of highly affine and selective dopamine D3 receptor ligands using privileged scaffolds of biogenic amine GPCR ligands

A series of compounds containing privileged scaffolds of the known histamine H1 receptor antagonists cetirizine, mianserin, ketotifen, loratadine, and bamipine were synthesized for further optimization as ligands for the related biogenic amine binding dopamine D3 receptor. A pharmacological screening was carried out at dopamine D2 and D3 receptors. In the preliminary testing various ligands have shown moderate to high affinities for dopamine D3receptors, for example, N-(4-{4-[benzyl(phenyl)amino]piperidin-1-yl}butylnaphthalen-2-carboxamide (19a) (hD3 Ki = 0.3 nM; hD2 Ki = 703 nM), leading to a selectivity ratio of 2343.