10256-01-6

Usage

Uses

Used in Pharmaceutical Industry:
1,3-DI-MORPHOLIN-4-YL-PROPANE-1,3-DIONE is used as a reactant for the synthesis of pharmaceutical compounds due to its unique chemical properties and reactivity. Its ability to participate in various chemical reactions allows for the creation of complex organic molecules that can be utilized in the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
1,3-DI-MORPHOLIN-4-YL-PROPANE-1,3-DIONE is used as a reactant in the production of agrochemicals for its capacity to contribute to the synthesis of compounds with potential applications in agriculture, such as pesticides, herbicides, and other crop protection agents. Its versatility in chemical reactions facilitates the development of innovative and effective agrochemical products.

InChI:InChI=1/C11H18N2O4/c14-10(12-1-5-16-6-2-12)9-11(15)13-3-7-17-8-4-13/h1-9H2

Upstream product

• 110-91-8 morpholine 
• 100626-07-1 4,4',4''-(2-oxo-propane-1,1,3-tricarbonyl)-tris-morpholine 
• 105-53-3 diethyl malonate 
• 117410-74-9 4,4'-<2-<(2-nitrofenil)tio>malonil>dimorfolina 
• 1663-67-8 malonoyl dichloride 

Downstream Products

• 117410-74-9 4,4'-<2-<(2-nitrofenil)tio>malonil>dimorfolina 
• 27759-71-3 Dithiomalonsaeuredimorpholid 
• 108401-64-5 4,4'-<2-(2-nitrofenossi)malonil>dimorfolina 
• 108401-68-9 4,4'-<2-(2-amminofenossi)malonil>dimorfolina 
• 117378-57-1 4,4'-<2-<(2-amminofenil)tio>malonil>dimorfolina 

Relevant academic research and scientific papers

Kinetic and Mechanistic Study of the Reaction between Dithiomalonamides and Diiodine. Crystal Structure of the Compounds 3,5-Bis(ethylamino)-1,2-dithiolylium Triiodide and 3,5-Bis(morpholino)-1,2-dithiolylium Iodide Monohydrate

The reaction of N,N'-diethyldithiomalonamide with I2 has been investigated spectrophotometrically.A kinetic study carried out with the stopped-flow technique has shown the transient formation of a 1:1 N,N'-diethyldithiomalonamide*I2 charge-transfer complex having a formation constant K1 = 2.3(3) x 103 dm3 mol-1 at 25 deg C.This is followed by an oxidation-reduction reaction leading to 3,5-bis(ethylamino)-1,2-dithiolylium iodide and HIn (n = 1 or 3), through a first- and a second-order process with respective rate constants at 25 deg C k1 = 0.84(7) s-1and k2 = 2.0(3) x 103 dm3 mol-1 s-1, consisting of an unassisted or I2 assisted heterolytic fission of the I-I bond as the slow step.Further associative equilibria of 3,5-bis(ethylamino)-1,2-dithiolylium iodide and HI with free I2 leading to the corresponding triiodides have also been observed, having formation constants, respectively, K2 = 6.2(7) x 105 dm3 mol-1 and K3 = 8.9(5) x 106 dm3 mol-1.All the kinetic and thermodynamic parameters were obtained by an expressly devised computational method based on nonlinear least-squares procedures.An X-ray crystal structure analysis of the title compounds, obtained as products of the reaction between I2 and RNR'C(S)CH2C(S)R'NR, showed that the crystals obtained in the RNR' = EtNH and I2 excess case are monoclinic, space group C2/m, with a = 13.643(6), b = 9.749(5), c = 11.879(6) Angstroem, β = 99.76(2) deg and Z = 4.The structure consists of chains running parallel to , where the 3,5-bis(ethylamino)-1,2-dithiolylium cations and triiodide anions are connected through two strong interactions involving the terminal iodide atom of the unsymmetrical I3- (I2...I- anion) and both the sulphur atoms of the disulphide group.In the RNR' = OC4H8N and 1:1 reagents ratio case the crystals are monoclinic, space group P21/c, with a = 9.256(4), b = 20.257(6), c = 8.483(4) Angstroem, β = 90.91(2) deg and Z = 4.The structure consists of layers, approximately parallel to (201), determined by contacts involving cations, iodide anions and water molecules.

2H-1,4-BENZOTIAZINE 3-(DIALCHILAMMINO)SOSTITUITE

Reaction of 2-aminothiophenol with N,N,N',N'-tetrasubstituted 2-bromomalonamides (I), in the presence of sodium hydroxide, gave 2-malonamides (II) which in turn were converted into N,N-dialkyl-3-(dialkylamino)-2H-benzothiazine-2-carbo