1025768-98-2Relevant articles and documents
Synthesis and antibacterial activity of a novel series of potent DNA gyrase inhibitors. Pyrazole derivatives
Tanitame, Akihiko,Oyamada, Yoshihiro,Ofuji, Keiko,Fujimoto, Mika,Iwai, Noritaka,Hiyama, Yoichi,Suzuki, Kenji,Ito, Hideaki,Terauchi, Hideo,Kawasaki, Motoji,Nagai, Kazuo,Wachi, Masaaki,Yamagishi, Jun-Ichi
, p. 3693 - 3696 (2007/10/03)
We have previously found that a pyrazole derivative 1 possesses antibacterial activity and inhibitory activity against DNA gyrase and topoisomerase IV. Here, we synthesized new pyrazole derivatives and found that 5-[(E)-2-(5-chloroindol-3-yl)vinyl]pyrazol