1025897-83-9

Upstream product

• 22049-02-1 2-methyl-5,6,7,8-tetrahydroquinolin-4(1H)-one 
• 169270-77-3 3-(bromomethyl)-11-(trityl-1H-tetrazol-5-yl)dibenzocyclohepten-5-one 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 169270-76-2 3-methyl-11-(trityl-1H-tetrazol-5-yl)dibenzocyclohepten-5-one 
• 169270-59-1 (RS)-7-methyl-5-oxo-10-phenylselenyl-10,11-dihydro-5H-dibenzocyclopentene-10-carbonitrile 
• 169270-75-1 3-methyl-11-(1H-tetrazol-5-yl)dibenzocyclohepten-5-one 
• 169270-60-4 7-methyl-5-oxo-5H-dibenzocycloheptene-10-carbonitrile 
• 26963-65-5 2-(2-Cyano-2-p-tolyl-ethyl)-benzoyl chloride 
• 26899-76-3 (RS)-7-methyl-5-oxo-10,11-dihydro-5H-dibenzocycloheptene-10-carbonitrile 
• 26925-62-2 (RS)-2-(2-cyano-2-p-tolylethyl)benzoic acid 
• 26926-15-8 (Z)-2-(2-cyano-2-p-tolylvinyl)benzoic acid 

Relevant academic research and scientific papers

Novel Angiotensin II Receptor Antagonists. Design, Synthesis, and in Vitro Evaluation of Dibenzocycloheptene and Dibenzooxepin Derivatives. Searching for Bioisosteres of Biphenylyltetrazole Using a Three-Dimensional Search Technique

Three-dimensional substructure searching (3D search), using the program MACCS-3D, was utilized for designing novel angiotensin II receptor antagonists which contain a bioisostere of the biphenylyltetrazole moiety of DuP 753.A 3D query was prepared from an