26963-65-5

Upstream product

• 26925-62-2 (RS)-2-(2-cyano-2-p-tolylethyl)benzoic acid 
• 26926-15-8 (Z)-2-(2-cyano-2-p-tolylvinyl)benzoic acid 
• 16859-59-9 3-hydroxy-1(3H)-isobenzofuranone 
• 2947-61-7 (4-methylphenyl)acetonitrile 

Downstream Products

• 1026038-27-6 2-Ethyl-4-[5-oxo-11-(1-trityl-1H-tetrazol-5-yl)-5H-dibenzo[a,d]cyclohepten-3-ylmethoxy]-quinoline-6-carboxylic acid ethyl ester 
• 1027516-72-8 3-(2-Ethyl-6-methoxy-[1,5]naphthyridin-4-yloxymethyl)-11-(1-trityl-1H-tetrazol-5-yl)-dibenzo[a,d]cyclohepten-5-one 
• 1027366-94-4 2,6-Dimethyl-4-[5-oxo-11-(1-trityl-1H-tetrazol-5-yl)-5H-dibenzo[a,d]cyclohepten-3-ylmethoxy]-nicotinic acid ethyl ester 
• 1026380-54-0 3-(2-Ethyl-5,6,7,8-tetrahydro-quinolin-4-yloxymethyl)-11-(1-trityl-1H-tetrazol-5-yl)-dibenzo[a,d]cyclohepten-5-one 
• 1027555-54-9 3-(2-Ethyl-quinolin-4-yloxymethyl)-11-(1-trityl-1H-tetrazol-5-yl)-dibenzo[a,d]cyclohepten-5-one 
• 1025897-83-9 3-(2-Methyl-5,6,7,8-tetrahydro-quinolin-4-yloxymethyl)-11-(1-trityl-1H-tetrazol-5-yl)-dibenzo[a,d]cyclohepten-5-one 
• 169270-79-5 methyl 2-<(tert-butoxycarbonyl)<(11-cyano-5-oxo-5H-dibenzocyclohepten-3-yl)methyl>amino>-3-nitrobenzoate 
• 169270-77-3 3-(bromomethyl)-11-(trityl-1H-tetrazol-5-yl)dibenzocyclohepten-5-one 
• 169270-76-2 3-methyl-11-(trityl-1H-tetrazol-5-yl)dibenzocyclohepten-5-one 
• 169270-80-8 methyl 2-<<(11-cyano-5-oxo-5H-dibenzocyclohepten-3-yl)methyl>amino>-3-nitrobenzoate 
• 169270-81-9 methyl 3-amino-2-<<(11-cyano-5-oxo-5H-dibenzocyclohepten-3-yl)methyl>amino>benzoate 
• 169270-59-1 (RS)-7-methyl-5-oxo-10-phenylselenyl-10,11-dihydro-5H-dibenzocyclopentene-10-carbonitrile 

Relevant academic research and scientific papers

Novel Angiotensin II Receptor Antagonists. Design, Synthesis, and in Vitro Evaluation of Dibenzocycloheptene and Dibenzooxepin Derivatives. Searching for Bioisosteres of Biphenylyltetrazole Using a Three-Dimensional Search Technique

Three-dimensional substructure searching (3D search), using the program MACCS-3D, was utilized for designing novel angiotensin II receptor antagonists which contain a bioisostere of the biphenylyltetrazole moiety of DuP 753.A 3D query was prepared from an