1025932-55-1

Basic information

• Product Name: N'-benzyl-N'-[3-hydroxy-2-(3-hydroxy-2-methyl-benzoylamino)-butyryl]-hydrazinecarboxylic acid tert-butyl ester
• CAS NO: 1025932-55-1
• Molecular Weight: 457.527
• Mol File: 1025932-55-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N'-benzyl-N'-[3-hydroxy-2-(3-hydroxy-2-methyl-benzoylamino)-butyryl]-hydrazinecarboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N'-benzyl-N'-[3-hydroxy-2-(3-hydroxy-2-methyl-benzoylamino)-butyryl]-hydrazinecarboxylic acid tert-butyl ester(1025932-55-1)
• EPA Substance Registry System: N'-benzyl-N'-[3-hydroxy-2-(3-hydroxy-2-methyl-benzoylamino)-butyryl]-hydrazinecarboxylic acid tert-butyl ester(1025932-55-1)

Safety Data

• Hazardous Substances Data: 1025932-55-1(Hazardous Substances Data)

Upstream product

• 603-80-5 3-hydroxy 2-methylbenzoic acid 
• 53370-84-6 N'-benzylhydrazinecarboxylic acid tert-butyl ester 
• 555-96-4 Benzylhydrazine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1026062-92-9 N-{1-[N-benzyl-N'-(2-hydroxy-ethyl)-hydrazinocarbonyl]-2-hydroxy-propyl}-3-hydroxy-2-methyl-benzamide 
• 1027596-05-9 N-[1-(N-benzyl-N'-hydroxymethyl-hydrazinocarbonyl)-2-hydroxy-propyl]-3-hydroxy-2-methyl-benzamide 
• 1027203-58-2 {N'-benzyl-N'-[3-hydroxy-2-(3-hydroxy-2-methyl-benzoylamino)-butyryl]-hydrazino}-acetic acid ethyl ester 
• 1026822-38-7 N'-benzyl-N'-[3-hydroxy-2-(3-hydroxy-2-methyl-benzoylamino)-butyryl]-hydrazinecarboxylic acid ethyl ester 

Relevant articles and documents

HIV protease inhibitors: Synthesis and activity of N-aryl-N′- hydroxyalkyl hydrazide pseudopeptides

We describe the synthesis and activities of a series of pseudopeptides containing an N-aryl-N′-hydroxyalkyl hydrazide core structure to inhibit human immunodeficiency virus protease and viral replication. Of the series, compound Hmb-Leu-N(Bzl)-N(CH2-CH-OH)-rPro-Boc (24) displayed the greatest inhibitory potency (IC50 1 μM) and exhibited enzymatic resistance and stability in vitro.