102594-06-9Relevant articles and documents
Diastereoselective synthesis of 3-(α-aryl)alkenylindoles from the direct dehydrative coupling of indoles and ketones: A synthetic and theoretical study
Barbero, Margherita,Marabello, Domenica,Dughera, Stefano,Sicari, Tiziana,Antenucci, Achille,Ghigo, Giovanni
, (2020/09/04)
A representative library of 3-(α-aryl)alkenylindoles has been prepared via a Br?nsted-acid catalysed dehydrative coupling reaction between alkyl aryl ketones and some indoles. An interesting diastereoselectivity has been observed and has been explained from a mechanistic point of view.
Bronsted acid ionic liquid catalyzed facile synthesis of 3-vinylindoles through direct C3 alkenylation of indoles with simple ketones
Taheri, Amir,Liu, Changhui,Lai, Bingbing,Cheng, Cheng,Pan, Xiaojuan,Gu, Yanlong
supporting information, p. 3715 - 3719 (2014/08/05)
A direct dehydrative coupling protocol for the synthesis of 3-vinylindoles using easily available indoles and simple ketones as substrates was developed with the aid of a sulfonyl-containing Bronsted acid ionic liquid. The salient features of this protoco