1025959-05-0

Basic information

• Product Name: 1-(2-Amino-2-methyl-propoxy)-4,4-diphenyl-butan-2-ol
• CAS NO: 1025959-05-0
• Molecular Weight: 313.44
• Mol File: 1025959-05-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-Amino-2-methyl-propoxy)-4,4-diphenyl-butan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Amino-2-methyl-propoxy)-4,4-diphenyl-butan-2-ol(1025959-05-0)
• EPA Substance Registry System: 1-(2-Amino-2-methyl-propoxy)-4,4-diphenyl-butan-2-ol(1025959-05-0)

Safety Data

• Hazardous Substances Data: 1025959-05-0(Hazardous Substances Data)

Upstream product

• 1027324-14-6 1-Bromo-4,4-diphenyl-butan-2-ol 
• 5409-60-9 4,4-diphenylbutan-2-one 
• 124-68-5 2-Amino-2-methyl-1-propanol 
• 54766-52-8 4,4-diphenyl-1,2-epoxybutane 

Downstream Products

• 149553-41-3 tert-butyl N-<1,1-dimethyl-2-(2-methylsulfonyl-4,4-diphenylbutyloxy)ethyl>carbamate 
• 149553-40-2 tert-butyl N-<2-(2-hydroxy-4,4-diphenylbutyloxy)-1,1-dimethylethyl>carbamate 

Relevant articles and documents

Agents for the treatment of overactive detrusor. IV. Synthesis and structure-activity relationships of cyclic analogues of terodiline

A series of pyrrolidine derivatives were synthesized and examined for inhibitory activity on detrusor contraction in vivo. Among those compounds, 5,5-dimethyl-2-(2,2-diphenylethyl)-3-isopropylidenepyrrolidine hydrochloride (41 · HCl), 2-(2,2-di(4-fluorophenyl)ethylene)-5,5-dimethyl-3-isopropylidenepyrrol idine hydrochloride (42 · HCl), (+)5,5-dimethyl-2-(N,N-diphenylaminomethyl)-3-isopropylidenepyrrolidin e hydrochloride (+)-(43a · HCl),(-)-5,5-dimethyl-2-(N,N-diphenylaminomethyl)-3-isopropylidenepyrr olidine hydrochloride (-)-(43a · HCl), and 2-(N,N-di(4-fluorophenyl)aminomethyl)-5,5-dimethyl-3-isopropylidenepyr rolidine methanesulfonate (43b · MsOH) showed stronger inhibitory activity on detrusor contraction than terodiline.