5409-60-9

Basic information

• Product Name: 4,4-DIPHENYL-2-BUTANONE
• Synonyms: 4,4'-DIPHENYL-2-BUTANONE;4,4-DIPHENYL-2-BUTANONE;4,4-diphenylbutan-2-one;4,4-Diphenyl-2-butanone,98%;1,1-Diphenyl-3-butanone
• CAS NO: 5409-60-9
• Molecular Formula: C₁₆H₁₆O
• Molecular Weight: 224.3
• EINECS: 226-482-4
• Product Categories: Aromatic Ketones (substituted)
• Mol File: 5409-60-9.mol
• Article Data: 77

Chemical Properties

• Melting Point: 170-171 °C
• Boiling Point: 328.8°Cat760mmHg
• Flash Point: 139.7°C
• Appearance: /
• Density: 1.037g/cm³
• CAS DataBase Reference: 4,4-DIPHENYL-2-BUTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DIPHENYL-2-BUTANONE(5409-60-9)
• EPA Substance Registry System: 4,4-DIPHENYL-2-BUTANONE(5409-60-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 5409-60-9(Hazardous Substances Data)

Usage

Uses

4,4-Diphenyl-2-butanone was used as a reagent in the efficient synthesis and ring opening reactions of monofluorinated epoxides.

Synthesis Reference(s)

The Journal of Organic Chemistry, 38, p. 4213, 1973 DOI: 10.1021/jo00963a030Synthesis, p. 575, 1984Tetrahedron Letters, 20, p. 4591, 1979

Upstream product

• 122-57-6 1-Phenylbut-1-en-3-one 
• 1896-62-4 (E)-benzalacetone 
• 591-50-4 iodobenzene 
• 78-94-4 methyl vinyl ketone 
• 591-51-5 phenyllithium 
• 19672-37-8 3-benzhydryl-pentane-2,4-dione 
• 960-71-4 triphenylborane 
• 143-66-8 sodium tetraphenyl borate 
• 98-80-6 phenylboronic acid 
• 934-56-5 trimethyl(phenyl)stannane 
• 7647-01-0 hydrogenchloride 
• 7446-70-0 aluminium trichloride 
• 71-43-2 benzene 
• 108-86-1 bromobenzene 

Downstream Products

• 110246-10-1 1-(1-methyl-3,3-diphenyl-propyl)-piperidine 
• 65190-71-8 [2-(2,2-diphenyl-ethyl)-[4]quinolyl]-phenyl-amine 
• 101596-92-3 3-oxo-5,5-diphenyl-valeraldehyde 
• 29869-86-1 4-(4-chlorophenyl)-4-phenylbutane-2-one 
• 36317-60-9 4,4-diphenyl-2-butanol 
• 36317-57-4 4,4-diphenyl-butan-2-one oxime 
• 146537-63-5 1,5-diphenyl-2,4-pentadien-1-one oxime 
• 133709-11-2 N-(1,1-Dimethyl-3,3-diphenyl-propyl)-acetamide 
• 56740-59-1 1,1-Dimethyl-3,3-diphenylpropylamine 
• 1600491-53-9 1-(1-(4,4-diphenylbutan-2-yl)piperidin-4-yl)-3-ethylindolin-2-one 

Relevant articles and documents

Arylboronic Acid Catalyzed Dehydrative Mono-/Dialkylation Reactions of β-Ketoacids and Alcohols

The dehydrative mono-/dialkylation reactions of alcohols and β-ketoacids were realized under arylboronic acid catalysis, furnishing a series of β-aryl ketones and β-ketoesters in yields of 15–99%, with CO2 and H2O being the byproduct

Photocatalytic Hydroacylation of Alkenes by Directly Using Acyl Oximes

Acyl oximes are directly used as the acyl radical precursors in the hydroacylation reactions for the first time. In this work, acyl radicals can be effectively generated via β-scission of a phosphoranyl radical under photocatalytic conditions. As a result, the hydroacylation of alkenes triggered by the resulting acyl radicals leads to facile syntheses of a range of valuable ketones.

Rhenium-catalyzed α-alkylation of enol acetates with alcohols or ethers

When benzylic and allylic alcohols were treated with enol acetate in the presence of a catalytic amount of a rhenium complex, ReBr(CO)5, the carbon-carbon bond formation of the alcohols and enol acetate smoothly proceeded to give the corresponding ketones and aldehyde in moderate to good yields. For the reaction of allylic alcohols, γ,δ-unsaturated carbonyl compounds were obtained in good yields. When ethers were used instead of alcohols as the alkylated agent, two alkyl moieties on the ethers were utilized on the reaction.