10264-55-8

Usage

Uses

Used in Chemical Industry:
3-Ethylcyclopentanone is used as a chemical reagent for various chemical synthesis processes. Its ability to react with different types of reagents makes it a valuable component in the production of a wide range of chemicals.
Used in Pharmaceutical Industry:
3-Ethylcyclopentanone serves as a pharmaceutical reagent, playing a crucial role in the development and synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be used in the creation of new drugs and medications.
Used as a Pharmaceutical Intermediate:
In addition to its role as a reagent, 3-Ethylcyclopentanone is also utilized as a pharmaceutical intermediate. This means that it is an essential compound in the multi-step synthesis of various pharmaceutical products, contributing to the overall structure and function of the final drug.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 379, 1984 DOI: 10.1016/S0040-4039(00)99888-5

InChI:InChI=1/C7H12O/c1-2-6-3-4-7(8)5-6/h6H,2-5H2,1H3/t6-/m0/s1

Upstream product

• 5842-19-3 3-ethyladipic acid 
• 930-30-3 cyclopent-2-enone 
• 97-94-9 triethyl borane 
• 14252-62-1 4-vinylcyclopent-2-en-1-one 
• 35562-23-3 1-Chlor-2-ethylcyclopent-3-en-5-on 
• 5682-69-9 3-ethyl-cyclopent-2-enone 
• 84602-27-7 3-Acetylcyclopentanone 
• 35522-40-8 1-diazo-heptan-2-one 
• 557-20-0 diethylzinc 
• 695-56-7 1,4-dioxaspiro[4.4]non-6-ene 
• 2386-64-3 ethylmagnesium chloride 
• 811-49-4 ethyllithium 
• 249904-46-9 1-Nitrooxy-bicyclo[2.2.1]heptane 
• 51566-98-4 1-norbornyl alcohol 

Downstream Products

• 50549-26-3 4-ethyl-2-piperidinone 
• 10264-55-8 (R)-3-ethylcyclopentanone 
• 10264-55-8 (S)-3-ethylcyclopentanone 
• 634585-94-7 C₂₁H₂₆N₄O₄ 
• 634586-05-3 2-(3-ethylcyclopentyl)-5-methyl-2,4-dihydroxypyrazol-3-one 
• 1438288-24-4 1-(4-chlorophenethyl)-3-(3-ethylcyclopentyl)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 1438288-23-3 1-(3-chlorophenethyl)-3-(3-ethylcyclopentyl)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 1438289-02-1 3-ethyl-N-((S)-1-phenylethyl)cyclopentan-1-amine 

Relevant academic research and scientific papers

Copper-catalyzed enantioselective conjugate addition of triethylaluminum to 2-cyclopentenone

Bidentate phosphites were prepared starting from BINOL, H8-BINOL or 3,3′, 5,5′-tetra-tert-butyl-2,2′-biphenol. Utilization of these ligands in the copper-catalyzed enantioselective conjugate addition of triethylaluminum to 2-cyclopentenone affo

Enantioselectivity switch in copper-catalyzed conjugate addition reactions under the influence of a chiral N-heterocyclic carbene-silver complex

The asymmetric 1,4-addition of Et2Zn to 2-cyclohexen-1-one using a Cu(i) salt/N-heterocyclic carbene (NHC)-Ag complex catalytic system afforded optically active 3-ethylcyclohexanone. The reversal of enantioselectivity using the same catalytic s

Highly enantioselective copper-catalyzed 1,4-conjugate addition of diethylzinc to cyclic enones and αβ-unsaturated lactones

A significant improvement in enantioselectivity has been achieved in the 1,4-additions of diethylzinc to 2-cyclopentenone, 2-cyclohexenone and 5,6-hydro-2H-pyran-2-one (up to 93%, 98% and 94% ee, respectively) by using a chiral diphosphite-copper catalyst under suitable reaction conditions.

Tropanes as scaffolds for phosphorus-olefin ligands and their application in asymmetric catalysis

Tropane-derived phosphorus-olefin hybrid ligands bearing various combinations of P-units (chiral BINOL-derived units/achiral PPh 2-units) with a tropene skeleton (chiral/achiral) have been synthesized and used in Cu-catalysed conjugate 1,4-addi

Chiral phosphite ligands derived from l-(+)-tartaric acid: Synthesis and application in the Cu-catalyzed 1,4-conjugate addition of organozincs to cyclic enones

A new series of chiral phosphite ligands derived from readily available l-(+)-tartaric acid and binaphthol derivatives were designed and prepared in convenient synthetic routes. These ligands were successfully employed in the Cu-catalyzed asymmetric conju

Enantioselective conjugate addition of dialkylzinc to cyclic enones catalyzed by chiral binaphthyldiamine-copper(I) complexes

The enantioselective conjugate addition of dialkylzinc (R2Zn) to cyclic enones was examined using chiral binaphthyldiamine-copper(I) catalysts. Under the present reaction conditions, chiral C2-symmetric [RZn(II)]2-diamine-

Synthesis of epimer of Taniaphos ligand

The spatial arrangement of groups within a chiral ligand is essential for its catalytic performance. This work describes convenient synthesis of (R,Sp)-1-(2-(diphenylphosphano)ferrocenyl)-1-(2-diphenylphosphanophenyl)-N,N-dimethylmethanamine, a

Cu-catalyzed asymmetric conjugate addition of dialkylzincs to enones using a (±)- trans -1,2-cyclohexanediamine-based bis(NHC) derived from l -leucinol

A hydroxyamide-functionalized azolium salt as the precursor of a (±)-trans-1,2-cyclohexanediamine-based bis(NHC) ligand was designed and synthesized from readily accessible l-leucinol. The combination of a Cu salt with this chiral ligand precursor promote

Imido-P(v) trianion supported enantiopure neutral tetrahedral Pd(II) cages

Charge-neutral chiral hosts are attractive due to their ability to recognize a wide range of guest functionalities and support enantioselective processes. However, reports on such charge-neutral cages are very scarce in the literature. Here, we report an enantiomeric pair of tetrahedral Pd(ii) cages built from chiral tris(imido)phosphate trianions and oxalate linkers, which exhibit enantioselective separation capabilities for epichlorohydrin, β-butyrolactone, and 3-methyl- and 3-ethyl cyclopentanone.

Enantioselective conjugate addition of diethylzinc to cyclic enones with chiral aryl diphosphite-copper catalysts

A series of C2-symmetric aryl diphosphites based on chiral binaphthol were prepared and their copper complexes were found to be efficient catalysts for the conjugate addition of diethylzinc to cyclic enones. Good enantioselectivities (up to 89.8 and 88.7% ee, respectively) were obtained in the conjugate addition of diethylzinc to 2-cyclohexenone and 2- cyclopentenone.