1026561-42-1

Basic information

• Product Name: 4-(1H-Indol-3-yl)-1-[4-(4-methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butan-1-one
• Synonyms: 4-(1H-Indol-3-yl)-1-[4-(4-methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butan-1-one
• CAS NO: 1026561-42-1
• Molecular Weight: 374.483
• Mol File: 1026561-42-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(1H-Indol-3-yl)-1-[4-(4-methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-Indol-3-yl)-1-[4-(4-methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butan-1-one(1026561-42-1)
• EPA Substance Registry System: 4-(1H-Indol-3-yl)-1-[4-(4-methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butan-1-one(1026561-42-1)

Safety Data

• Hazardous Substances Data: 1026561-42-1(Hazardous Substances Data)

Upstream product

• 302924-67-0 tert-butyl 4-hydroxy-4-(4-methoxyphenyl)-1-piperidinecarboxylate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 6717-00-6 1-benzyl-4-(4-methoxy-phenyl)-piperidin-4-ol 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 133-32-4 4-indol-3-yl-butyric acid 
• 143017-63-4 4-(4-methoxyphenyl)-1,2,3,6-tetrahydropyridine hydrochloride 

Downstream Products

• 143682-48-8 3-{4-[4-(4-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole 

Relevant articles and documents

Synthesis and dopaminergic activity of some 3-(1,2,3,6-tetrahydro-1- pyridylalkyl)indoles. A novel conformational model to explain structure- activity relationships

The synthesis and dopaminergic properties of a novel type of dopamine agonist is described. The number and kind of essential structural elements differ significantly from that of the rigid apomorphine-type dopamine agonists. Using standard molecular modeling techniques, a conformational model is developed proposing a U-shaped conformation which might be energetically preferred through aromatic π-π-interactions between both of the electron rich aromatic structural elements of this class of compounds. Superimposition of conformations of the lead compound 28 with apomorphine yields a novel model explaining the atypical structure-activity relationships found in this class of indolealkylamines.