1026692-44-3Relevant articles and documents
Highly potent triazole-based tubulin polymerization inhibitors
Zhang, Qiang,Peng, Youyi,Wang, Xin I.,Keenan, Susan M.,Arora, Sonia,Welsh, William J.
, p. 749 - 754 (2007/10/03)
We describe the synthesis and biological evaluation of a series of tubulin polymerization inhibitors that contain the 1,2,4-triazole ring to retain the bioactive configuration afforded by the cis double bond in combretastatin A-4 (CA-4). Several of the su