155754-75-9Relevant academic research and scientific papers
Highly potent triazole-based tubulin polymerization inhibitors
Zhang, Qiang,Peng, Youyi,Wang, Xin I.,Keenan, Susan M.,Arora, Sonia,Welsh, William J.
, p. 749 - 754 (2007/10/03)
We describe the synthesis and biological evaluation of a series of tubulin polymerization inhibitors that contain the 1,2,4-triazole ring to retain the bioactive configuration afforded by the cis double bond in combretastatin A-4 (CA-4). Several of the su
Cell proliferation inhibitors
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, (2008/06/13)
Compounds having formula (I) inhibit cellular proliferation. Processes for the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds are disclosed.
