1026968-07-9Relevant academic research and scientific papers
Design, synthesis, and evaluation of benzothiadiazepine hydroxamates as selective tumor necrosis factor-α converting enzyme inhibitors
Cherney, Robert J.,Duan, James J.-W.,Voss, Matthew E.,Chen, Lihua,Wang, Li,Meyer, Dayton T.,Wasserman, Zelda R.,Hardman, Karl D.,Liu, Rui-Qin,Covington, Maryanne B.,Qian, Mingxin,Mandlekar, Sandhya,Christ, David D.,Trzaskos, James M.,Newton, Robert C.,Magolda, Ronald L.,Wexler, Ruth R.,Decicco, Carl P.
, p. 1811 - 1823 (2007/10/03)
Elevated levels of tumor necrosis factor-α (TNF-α) have been associated with several inflammatory diseases, and therefore, strategies for its suppression have become important targets in drug discovery. Our efforts to suppress TNF-α have centered on the i
