10272-06-7

Basic information

• Product Name: 3-chloro-5-methoxyaniline
• Synonyms: 3-chloro-5-methoxyaniline;Einecs 233-614-4;3-chloro-5-Methoxy-benzenaMine;3-Chloro-5-aminoanisole
• CAS NO: 10272-06-7
• Molecular Formula: C₇H₈ClNO
• Molecular Weight: 157.59752
• EINECS: 233-614-4
• Mol File: 10272-06-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 33 °C
• Boiling Point: 280.3°Cat760mmHg
• Flash Point: 123.3°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 0.00381mmHg at 25°C
• Refractive Index: 1.572
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 3.12±0.10(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: 3-chloro-5-methoxyaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-5-methoxyaniline(10272-06-7)
• EPA Substance Registry System: 3-chloro-5-methoxyaniline(10272-06-7)

Safety Data

• Hazardous Substances Data: 10272-06-7(Hazardous Substances Data)

Usage

Uses

3-Chloro-5-methoxyaniline is an intermediate used in the synthetic preparation of various pharmaceutical goods.

InChI:InChI=1/C7H8ClNO/c1-10-7-3-5(8)2-6(9)4-7/h2-4H,9H2,1H3

Upstream product

• 618-86-0 1-chloro-3,5-dinitrobenzene 
• 99-65-0 meta-dinitrobenzene 
• 33719-74-3 3,5-dichloroanisole 
• 55910-07-1 1-chloro-3-methoxy-5-nitrobenzene 

Downstream Products

• 883195-40-2 3-amino-5-chlorophenol 
• 425666-39-3 N-(5-chloro-2-methoxyphenyl)-4-{[(3,4-dimethylphenyl)(methylsulfonyl)amino]methyl}benzamide 
• 6324-16-9 7-chloro-4-hydroxy-5-methoxy-quinoline-3-carboxylic acid ethyl ester 
• 52780-23-1 chloro-3,5-dihydroxybenzene 
• 62606-11-5 (3-Chloro-5-methoxy-phenyl)-(2,4,6-trinitro-phenyl)-amine 
• 855654-74-9 (3-chloro-5-methoxy-anilinomethylene)-malonic acid diethyl ester 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS OF USE

Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides

The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of each group are described in the specification. The compound represented by formula I can be used as a ligand in copper-catalyzed coupling reaction of aryl halides for the formation of C—N, C—O and C—S bonds.

QUINUCLIDINES FOR MODULATING ALPHA 7 ACTIVITY

Provided are substituted quinuclidine compounds, pharmaceutical compositions comprising such compounds, and methods of modulating α7 nicotinic acetylcholine receptors and treating neurological disorders using such compounds.