174913-12-3

Usage

Uses

Used in Pharmaceutical Industry:
1-Bromo-3-chloro-5-methoxybenzene is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex organic molecules, contributing to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 1-bromo-3-chloro-5-methoxybenzene is utilized as an intermediate in the production of agrochemicals, potentially enhancing the effectiveness of pesticides and other agricultural chemicals.
Used in Organic Chemistry Research:
1-Bromo-3-chloro-5-methoxybenzene serves as a reagent in organic chemistry reactions such as nucleophilic aromatic substitution and cross-coupling reactions, facilitating the synthesis of a wide range of organic compounds for research and development purposes.
Used in Dye and Pigment Production:
1-BROMO-3-CHLORO-5-METHOXYBENZENE is used as a building block in the production of dyes and pigments, where its unique structure contributes to the color and stability of the final products.
Used in Polymer Industry:
1-Bromo-3-chloro-5-methoxybenzene is also utilized in the polymer industry, where it can be incorporated into polymer chains to modify their properties, such as stability, solubility, and reactivity, for specific applications.

InChI:InChI=1S/C7H6BrClO/c1-10-7-3-5(8)2-6(9)4-7/h2-4H,1H3

Upstream product

• 108-43-0 3-monochlorophenol 
• 6575-00-4 3,5-dichlorobenzonitrile 
• 124-41-4 sodium methylate 
• 33863-76-2 1-bromo-3-chloro-5-fluorobenzene 
• 929626-16-4 2-(3-chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 55910-07-1 1-chloro-3-methoxy-5-nitrobenzene 
• 56962-04-0 3-bromo-5-chlorophenol 
• 77-78-1 dimethyl sulfate 
• 10272-06-7 3-chloro-5-methoxyaniline 
• 87504-69-6 3-chloro-2,4,5,6-tetrabromophenol 

Downstream Products

• 860734-36-7 5-bromo-3-chloro-2,4-dinitro-anisole 
• 473923-96-5 3-chloro-5-methoxybenzonitrile 
• 56962-04-0 3-bromo-5-chlorophenol 
• 61150-48-9 4-chloro-3-methoxybenzenethiol 
• 65262-96-6 3-chloro-5-methoxyphenol 
• 1257087-39-0 4-[(4-chloro-3-hydroxyphenyl)thio]benzoic acid 
• 1257087-38-9 4-[(4-chloro-3-methoxyphenyl)thio]benzoic acid 
• 1257087-40-3 4-[(3-acetoxy-4-chlorophenyl)thio]benzoic acid 
• 1257086-27-3 (11β,17α)-17-{[(cyanomethyl)thio]carbonyl}-9-fluoro-11-hydroxy-3-oxoandrosta-1,4-dien-17-yl 4-[(4-chloro-3-hydroxyphenyl)thio]benzoate 
• 1093988-12-5 3-chloro-5-({6-chloro-3-[(5-{3-[(difluoromethyl)oxy]phenyl}-1,3,4-oxadiazol-2-yl)methyl]-2-fluorophenyl}oxy)benzonitrile 
• 1093988-13-6 2-({3-[(3-bromo-5-chlorophenyl)oxy]-4-chloro-2-fluorophenyl}methyl)-5-{3-[(difluoromethyl)oxy]phenyl}-1,3,4-oxadiazole 
• 1093988-10-3 3-chloro-5-{[6-chloro-3-({5-[3-(dimethylamino)phenyl]-1,3,4-oxadiazol-2-yl}methyl)-2-fluorophenyl]oxy}benzonitrile 
• 1093988-11-4 3-[5-({3-[(3-bromo-5-chlorophenyl)oxy]-4-chloro-2-fluorophenyl}methyl)-1,3,4-oxadiazol-2-yl]-N,N-dimethylaniline 
• 1093988-08-9 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(2-fluoro-3-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 

Relevant academic research and scientific papers

Meta halogenation of 1,3-disubstituted arenes via iridium-catalyzed arene borylation

We report the meta halogenation of 1,3-disubstituted arenes to form 3,5-disubstituted aryl bromides and chlorides by using iridium-catalyzed arene borylation chemistry. Iridium-catalyzed borylation of arenes with B2pin2, followed by reaction of the boronic ester with copper(II) bromide or chloride converts arylboronic esters to the corresponding aryl halides. A variety of arenes containing alkoxy, alkyl, halogen, nitrile, ester, amide, and pivaloyl and TIPS-protected alcohols were converted to the corresponding 3,5-disubstituted aryl bromides and chlorides in yields ranging from 46% to 85%. In addition, 2,6-disubstituted and 3-substituted pyridines were converted to the 4-halo and 5-halopyridines, respectively. The utility of this methodology was demonstrated by the formal conversion of nicotine to Altinicline in three steps with an overall yield of 61% using meta bromination of nicotine as the first step. Copyright

Non-nucleoside reverse transcriptase inhibitors

The present invention provides compounds for treating or preventing an HIV infection, or treating AIDS or ARC comprising administering a compound according to formula I where Ar, R1-R5, R7a, R7b, R7c, R8-R10, X1, X2 m, n, o and p are as defined herein.

Pyrazole derivatives

This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such, the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).