65262-96-6

Basic information

• Product Name: 3-chloro-5-methoxyphenol
• Synonyms: 3-Methoxy-5-chlorophenol;3-Chloro-5-methoxyphenol,99%;Einecs 265-661-1; 65262-96-6
• CAS NO: 65262-96-6
• Molecular Formula: C₇H₇ClO₂
• Molecular Weight: 158.59
• EINECS: 265-661-1
• Mol File: 65262-96-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 99℃
• Boiling Point: 265.3°Cat760mmHg
• Flash Point: 114.2°C
• Appearance: /
• Density: 1.28g/cm³
• Vapor Pressure: 0.00564mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-chloro-5-methoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-5-methoxyphenol(65262-96-6)
• EPA Substance Registry System: 3-chloro-5-methoxyphenol(65262-96-6)

Safety Data

• Hazardous Substances Data: 65262-96-6(Hazardous Substances Data)

Usage

General Description

3-chloro-5-methoxyphenol, also known as 3-Chloro-5-methoxyphenol, is a chemical compound with the molecular formula C7H7ClO2. It is a phenolic compound that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. This chemical is a white to yellow solid at room temperature and is soluble in organic solvents. It is often used as a building block in the production of various chemical compounds due to its reactivity and versatility. 3-chloro-5-methoxyphenol has also been studied for its antimicrobial and antioxidant properties and has potential applications in the fields of medicine and food preservation.

InChI:InChI=1/C7H7ClO2/c1-10-7-3-5(8)2-6(9)4-7/h2-4,9H,1H3

Upstream product

• 929626-16-4 2-(3-chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 174913-12-3 1-bromo-3-chloro-5-methoxybenzene 
• 33719-74-3 3,5-dichloroanisole 
• 2845-89-8 1-chloro-3-methoxy-benzene 
• 124-41-4 sodium methylate 
• 10272-06-7 3-chloro-5-methoxyaniline 

Downstream Products

• 65262-78-4 N-t-Butyl-3-(3-chloro-5-methoxyphenoxy)-benzamid 
• 65262-76-2 N-ethyl-3-(3-chloro-5-methoxyphenoxy)benzamide 
• 65262-77-3 N-Isopropyl-3-(3-chloro-5-methoxyphenoxy)-benzamid 
• 236112-47-3 1-Benzyloxy-3-chloro-5-methoxy-benzene 
• 68969-28-8 2-(3-chloro-5-methoxy)phenoxy butyric acid 
• 920036-08-4 3-chloro-5-(3-chloro-5-hydroxyphenoxy)benzonitrile 
• 440123-64-8 3-chloro-5-methoxy-2-nitro-phenol 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 98273-26-8 2,3,4-trichloro-5-methoxy-phenol 
• 140155-06-2 1-(4-chloro-2-hydroxy-6-methoxyphenyl)ethanone 
• 1404515-97-4 C₁₆H₁₇ClN₂O₃ 
• 1404516-58-0 2-chloro-4-(3-chloro-5-methoxyphenoxy)pyridine 
• 920035-44-5 3-(3-chloro-5-methoxyphenoxy)benzonitrile 
• 920036-16-4 1-chloro-3-methoxy-5-phenoxybenzene 

Relevant articles and documents

Derivatives of m-Guaiacol, Their Preparation and Their Uses

The invention concerns derivatives of m-guaiacol, their preparation and their uses as biocides, in particular as antibacterials or disinfectants.

Biocatalytic Properties and Structural Analysis of Phloroglucinol Reductases

Phloroglucinol reductases (PGRs) are involved in anaerobic degradation in bacteria, in which they catalyze the dearomatization of phloroglucinol into dihydrophloroglucinol. We identified three PGRs, from different bacterial species, that are members of the family of NAD(P)H-dependent short-chain dehydrogenases/reductases (SDRs). In addition to catalyzing the reduction of the physiological substrate, the three enzymes exhibit activity towards 2,4,6-trihydroxybenzaldehyde, 2,4,6-trihydroxyacetophenone, and methyl 2,4,6-trihydroxybenzoate. Structural elucidation of PGRcl and comparison to known SDRs revealed a high degree of conservation. Several amino acid positions were identified as being conserved within the PGR subfamily and might be involved in substrate differentiation. The results enable the enzymatic dearomatization of monoaromatic phenol derivatives and provide insight into the functional diversity that may be found in families of enzymes displaying a high degree of structural homology.

THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS

The present invention provides thiazole compounds of Formula I or its pharmaceutically acceptable salts, prodrugs, solvates, N-oxide thereof; solvates of pharmaceutically acceptable salts and N-oxides; pharmaceutically acceptable salts of N-oxides, or prodrugs; or combination or mixtures thereof; (I) The present invention further provides a method for preventing or treating a condition that responds to an Acetyl-CoA Carboxylase (ACC) inhibitor by using compounds of formula (I) or ), its pharmaceutically acceptable salts, prodrugs, solvates, N-oxide thereof; solvates of pharmaceutically acceptable salts and N-oxides; pharmaceutically acceptable salts of N-oxides, or prodrugs; or combination or mixtures thereof.