10272-10-3Relevant academic research and scientific papers
On the Reaction of Malononitrile with Acetylacetone
Kalita,Kim
, p. 1565 - 1568 (2018)
The reaction of malononitrile with acetylacetone in alkaline medium afforded a mixture of 2-amino-4,6-dimethylbenzene-1,3-dicarbonitrile and 4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile, whereas only the latter was formed in alcoholic medium in the absence of a catalyst. The alkylation of 4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile with allyl bromide gave a mixture of N- and O-allyl derivatives.
Synthesis of Fluorescent 2,6-Dicyano-3,5-Disubstituted Anilines Using Cellulose Sulfuric Acid in Aqueous Media
Zonouzi, Afsaneh,Izakian, Zakieh,Abdi, Khosrou,Ng, Seik Weng
, p. 355 - 360 (2016)
The synthesis of some fluorescent 2,6-dicyano-3,5-disubstituted anilines using cellulose sulfuric acid (Cellulose-SA) as an environmentally benign catalyst in H2O is described. The one-pot reaction of 1,3-diketone and three equiv. of malononitrile was carried out in the presence of one equiv. of a secondary amine, Cellulose-SA as catalyst, and H2O as solvent. The photophysical properties (λAbs., λFlu.) of the synthesized compounds in CH2Cl2, MeCN, and MeOH have been measured. The emission spectra of the new compounds in the solid state are also reported.
SYNTHESIS OF 4-AMINO-8-CYANOQUINAZOLINES FROM ENONES AND ENALS
Victory, Pedro,Borrell, Jose I.,Vidal-Ferran, Anton,Montenegro, Elvira,Jimeno, M. Luisa
, p. 2273 - 2280 (2007/10/02)
The treatment in a sodium methoxide/methanol solution of α,β-unsaturated enones or aldehydes with propanedinitrile in a 1:2 molar ratio led to 2-aminobenzene-1,3-dicarbonitriles.These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.
