1027232-20-7

Upstream product

• 321569-86-2 2,4,2',4'-tetrakis(benzyloxy)-6'-hydroxy-3'-iodochalcone 
• 321569-81-7 2',4'-bis(benzyloxy)-3'-iodo-6'-(methoxymethoxy)acetophenone 
• 321569-79-3 2',4'-dihydroxy-3'-iodo-6'-(methoxymethoxy)acetophenone 
• 67052-53-3 4',6'-bis(benzyloxy)-2'-(methoxymethoxy)acetophenone 
• 71386-98-6 2',4'-dihydroxy-6'-(methoxymethoxy)acetophenone 
• 67-56-1 methanol 
• 844868-34-4 6'-acetoxy-2,4,2',4'-tetrakis(benzyloxy)-3'-iodochalcone 

Downstream Products

• 321569-95-3 2',4',5,7-tetrakis(benzyloxy)-6-iodoisoflavone 
• 41743-56-0 luteone 
• 41628-68-6 2',4',5,7-tetraacetoxy-6-(3-methyl-2-butenyl)isoflavone 
• 91681-62-8 2',4',5,7-tetrahydroxy-6-(3-hydroxy-3-methylbutyl)isoflavone 
• 321570-06-3 2',4',7-tris(benzoyloxy)-5-hydroxy-6-(3-methyl-2-butenyl)isoflavone 
• 321570-01-8 2',4',7-tris(benzoyloxy)-5-hydroxy-6-(3-hydroxy-3-methylbutyl)isoflavone 
• 321569-98-6 2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone 
• 321570-10-9 2',4',7-tris(benzoyloxy)-6-(3-methyl-2-butenyl)-5-tosyloxyisoflavone 
• 321570-04-1 2',4',7-tris(benzoyloxy)-6-(3-hydroxy-3-methylbutyl)-5-tosyloxyisoflavone 

Relevant academic research and scientific papers

Regioselective synthesis of 6-alkyl- and 6-prenylpolyhydroxyisoflavones and 6-alkylcoumaronochromone derivatives

The palladium-catalyzed coupling reaction of 6-iodoisoflavone, prepared from 3′-iodoacetophenone derivative, with 2-methyl-3-butyn-2-ol gave 6-alkynylisoflavone derivative, which was hydrogenated to give 6-alkylhydroxyisoflavone (luteone hydrate) (2). Dehydration of 2 gave 2′,4′,5,7-tetrahydroxy-6-prenylisoflavone (luteone) (1). Wighteone hydrate (3) was also synthesized from 6-iodotris(benzyloxy)isoflavone in a similar manner. 6-Alkyl-4′5,7-trihydroxy-coumaronochromone (4) was synthesized by oxidative cyclization of 2 with o-chloranil.