1027247-32-0

Basic information

• Product Name: 4-bromo-1-(3-cyano-phenyl)-1H-pyrrole-2-carboxylic acid (2'-tert-butylsulfamoyl-biphenyl-4-yl)-amide
• Synonyms: 4-bromo-1-(3-cyano-phenyl)-1H-pyrrole-2-carboxylic acid (2'-tert-butylsulfamoyl-biphenyl-4-yl)-amide
• CAS NO: 1027247-32-0
• Molecular Weight: 577.502
• Mol File: 1027247-32-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromo-1-(3-cyano-phenyl)-1H-pyrrole-2-carboxylic acid (2'-tert-butylsulfamoyl-biphenyl-4-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-1-(3-cyano-phenyl)-1H-pyrrole-2-carboxylic acid (2'-tert-butylsulfamoyl-biphenyl-4-yl)-amide(1027247-32-0)
• EPA Substance Registry System: 4-bromo-1-(3-cyano-phenyl)-1H-pyrrole-2-carboxylic acid (2'-tert-butylsulfamoyl-biphenyl-4-yl)-amide(1027247-32-0)

Safety Data

• Hazardous Substances Data: 1027247-32-0(Hazardous Substances Data)

Upstream product

• 209958-48-5 1-(3-cyanophenyl)-2-formyl-4-bromopyrrole 
• 175134-98-2 3-(1H-pyrrol-1-yl)benzonitrile 
• 2237-30-1 m-cyanoaniline 
• 209958-45-2 1-(3-cyanophenyl)pyrrole-2-carboxaldehyde 
• 193006-34-7 4-(2'-tert-butylaminosulfonylphenyl)aniline 
• 1026040-98-1 4-bromo-1-(3-cyano-phenyl)-1H-pyrrole-2-carboxylic acid 

Relevant articles and documents

Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2′-(methylsulfonyl)-[1,1′-b iphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa

Factor Xa (fXa) plays a critical role in the coagulation cascade, serving as the point of convergence of the intrinsic and extrinsic pathways. Together with nonenzymatic cofactor Va and Ca2+ on the phospholipid surface of platelets or endotheli