1027270-48-9

Upstream product

• 404356-74-7 3-bromo-4-[1,3]dioxolan-2-yl-2-methoxy-phenol 
• 89984-24-7 2-bromo-4-hydroxy-3-methoxy-benzaldehyde 
• 404356-56-5 2-(4-allyloxy-2-bromo-3-methoxy-phenyl)-[1,3]dioxolane 

Downstream Products

• 404356-57-6 2-(5-allyl-4-benzyloxy-2-bromo-3-methoxy-phenyl)-[1,3]dioxolane 
• 404356-61-2 3-benzyloxy-6-[2-(tert-butyl-dimethyl-silanyloxy)-2-methoxycarbonyl-vinyl]-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-2-methoxy-benzoic acid methyl ester 
• 404356-62-3 7-benzyloxy-6-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-8-methoxy-1-oxo-1H-isochromene-3-carboxylic acid methyl ester 
• 404356-60-1 3-benzyloxy-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-6-[1,3]dioxolan-2-yl-2-methoxy-benzoic acid methyl ester 
• 1026785-84-1 3-benzyloxy-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-6-[1,3]dioxolan-2-yl-2-methoxy-benzoic acid 
• 404356-59-8 [2-(2-benzyloxy-4-bromo-5-[1,3]dioxolan-2-yl-3-methoxy-phenyl)-1-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethoxy]-tert-butyl-diphenyl-silane 
• 404356-77-0 3-benzyloxy-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-6-formyl-2-methoxy-benzoic acid methyl ester 
• 404356-76-9 3-(2-benzyloxy-4-bromo-5-[1,3]dioxolan-2-yl-3-methoxy-phenyl)-propane-1,2-diol 
• 404356-58-7 (2-benzyloxy-4-bromo-5-[1,3]dioxolan-2-yl-3-methoxy-phenyl)-acetaldehyde 

Relevant academic research and scientific papers

Studies in the total synthesis of heliquinomycinone: Proof of concept and assembly of a fully mature spirocyclization precursor

A strategy for the synthesis of heliquinomycin, a selective helicase inhibitor, hinges on the spirocyclization of precursor 3. Naphthofuran 1 and aldehyde 2 were readily prepared and used in the synthesis of 3. The key steps in the total synthesis of heli