404356-74-7

Upstream product

• 89984-24-7 2-bromo-4-hydroxy-3-methoxy-benzaldehyde 
• 107-21-1 ethylene glycol 

Downstream Products

• 404356-61-2 3-benzyloxy-6-[2-(tert-butyl-dimethyl-silanyloxy)-2-methoxycarbonyl-vinyl]-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-2-methoxy-benzoic acid methyl ester 
• 404356-62-3 7-benzyloxy-6-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-8-methoxy-1-oxo-1H-isochromene-3-carboxylic acid methyl ester 
• 404356-60-1 3-benzyloxy-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-6-[1,3]dioxolan-2-yl-2-methoxy-benzoic acid methyl ester 
• 1026785-84-1 3-benzyloxy-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-6-[1,3]dioxolan-2-yl-2-methoxy-benzoic acid 
• 404356-59-8 [2-(2-benzyloxy-4-bromo-5-[1,3]dioxolan-2-yl-3-methoxy-phenyl)-1-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethoxy]-tert-butyl-diphenyl-silane 
• 404356-77-0 3-benzyloxy-4-[2-(tert-butyl-diphenyl-silanyloxy)-2-(4,5,7,8,9-pentamethoxy-naphtho[2,3-b]furan-2-yl)-ethyl]-6-formyl-2-methoxy-benzoic acid methyl ester 
• 404356-76-9 3-(2-benzyloxy-4-bromo-5-[1,3]dioxolan-2-yl-3-methoxy-phenyl)-propane-1,2-diol 
• 404356-57-6 2-(5-allyl-4-benzyloxy-2-bromo-3-methoxy-phenyl)-[1,3]dioxolane 
• 404356-58-7 (2-benzyloxy-4-bromo-5-[1,3]dioxolan-2-yl-3-methoxy-phenyl)-acetaldehyde 
• 1027270-48-9 6-allyl-3-bromo-4-[1,3]dioxolan-2-yl-2-methoxy-phenol 
• 842150-47-4 methyl 7-benzyloxy-6-iodo-8-methoxy-1-oxo-1H-isochromene-3-carboxylate 
• 842150-44-1 methyl 6-formyl-3-hydroxy-4-iodo-2-methoxybenzoate 
• 842150-43-0 methyl 6-formyl-3-hydroxy-2-methoxybenzoate 
• 877662-87-8 methyl (E)-3-benzyloxy-4-iodo-2-methoxy-6-(2-methoxycarbonyl-2-tert-butyldimethylsiloxyethynyl)benzoate 

Relevant academic research and scientific papers

Towards the rubromycins: An efficient synthesis of a suitable isocoumarin precursor, its lactam analogue, and palladium-catalyzed couplings

6-Iodoisocoumarin 4 and its aza-analogue, 6-iodo-1-oxo-isoquinoline 29, were efficiently prepared from vanillin in seven and six steps, respectively. Key transformations in their syntheses were achieved by directed ortho-lithiation and variations of Horne

Studies in the total synthesis of heliquinomycinone: Proof of concept and assembly of a fully mature spirocyclization precursor

A strategy for the synthesis of heliquinomycin, a selective helicase inhibitor, hinges on the spirocyclization of precursor 3. Naphthofuran 1 and aldehyde 2 were readily prepared and used in the synthesis of 3. The key steps in the total synthesis of heli