1027341-17-8

Upstream product

• 1027341-08-7 2-(benzo[d]isothiazol-3-ylimino)thiazolidin-4-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 23031-78-9 3-aminobenzisothiazole 
• 69504-29-6 2-chloro-N-benzo[d]isothiazol-3-yl acetamide 

Relevant academic research and scientific papers

Heteroarylimino-4-thiazolidinones as inhibitors of cartilage degradation

2-Benzo[d]thiazolyl- and 2-benzo[d]isothiazolyl-imino-5-benzylidene-4- thiazolidinone derivatives were investigated as potential metalloproteinases (MMPs) inhibitors and evaluated for their antidegenerative activity on human chondrocyte cultures stimulate

2-thiazolylimino/heteroarylimino-5-arylidene-4-thiazolidinones as new agents with SHP-2 inhibitory action

SHP-2, a nonreceptor protein tyrosine phosphatase encoded by the PTPN11 gene, mediates cell signaling by growth factors and cytokines via the RAS/MAP kinase pathway. Somatic mutations in PTPN11 gene account for approximately 18% of juvenile myelomonocytic