1027356-55-3

Basic information

• Product Name: 2-BroMo-4-(tert-butyl)-6-nitroaniline
• Synonyms: 2-BroMo-4-(tert-butyl)-6-nitroaniline;2-Bromo-4-tert-butyl-6-nitro-phenylamine
• CAS NO: 1027356-55-3
• Molecular Formula: C₁₀H₁₃BrN₂O₂
• Molecular Weight: 273.12642
• Mol File: 1027356-55-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 61 °C
• Boiling Point: 317.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.465±0.06 g/cm3(Predicted)
• PKA: -1.77±0.25(Predicted)
• CAS DataBase Reference: 2-BroMo-4-(tert-butyl)-6-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-4-(tert-butyl)-6-nitroaniline(1027356-55-3)
• EPA Substance Registry System: 2-BroMo-4-(tert-butyl)-6-nitroaniline(1027356-55-3)

Safety Data

• Hazardous Substances Data: 1027356-55-3(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-(tert-butyl)-6-nitroaniline is a chemical compound that belongs to the class of nitroanilines, which are commonly used in the synthesis of pharmaceuticals, dyes, and agrochemicals. This specific compound is a derivative of aniline, with a bromine atom at the 2-position, a tert-butyl group at the 4-position, and a nitro group at the 6-position. It is primarily used as an intermediate in the synthesis of various organic compounds and can also be employed in chemical research and testing. Due to its specific structure and properties, 2-Bromo-4-(tert-butyl)-6-nitroaniline has potential applications in the development of new materials and pharmaceutical products. However, it is important to handle this compound with care and follow proper safety protocols due to its potential hazards.

Upstream product

• 769-92-6 4-tert-Butylaniline 
• 20330-45-4 4-tert-butylacetanilide 
• 40655-37-6 N-(4-(tert-butyl)-2-nitrophenyl)acetamide 
• 6310-19-6 4-tert-butyl-2-nitroaniline 

Downstream Products

• 156264-79-8 1-bromo-3-tert-butyl-5-nitrobenzene 
• 1353014-56-8 7-benzyl-1,13-dibromo-3,11-di-tert-butyl-6H-benzamidazo[2',1':3,4]pyrrolo[3',4':5,6]-pyrazino[1,2-a]benzimidazole-6,8(7H)-dione 

Relevant articles and documents

Molecular spur gears comprising triptycene rotators and bibenzimidazole-based stators

Dynamic gearing of molecular spur gears, the most common type of mechanical gear, is elucidated. Molecular design and conformational analysis show that derivatives of 4,4-bis(triptycen-9-ylethynyl)bibenzimidazole represent suitable constructs to investigate gearing behavior of collateral triptycene (Tp) groups. To test this design, DFT calculations (B97-D/Def2-TZVP) were employed and the results suggest that these molecules undergo geared rotation preferentially to gear slippage. Synthesis of derivatives was carried out, providing a series of molecular spur gears, including the first desymmetrized spur gear molecules, which were subsequently subjected to stereochemical analysis.

HETEROCYCLIC ANTIVIRAL COMPOUNDS

Compounds having the formula I wherein wherein R1, R2, R3, R4, X1, X2, X3 and X4 and as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.

ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF

This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.