1027379-76-5

Upstream product

• 6175-45-7 2,2-diethoxyacetophenone 
• 157422-73-6 N-allyl-2,2-diethoxy-1-phenylethylamine 
• 1027299-71-3 1-Benzyl-1H-indole-2-carboxylic acid allyl-(2,2-diethoxy-1-phenyl-ethyl)-amide 
• 1026063-21-7 (9-Benzyl-1-oxo-3-phenyl-1,9-dihydro-β-carbolin-2-yl)-acetaldehyde 
• 1027394-92-8 2-Allyl-9-benzyl-3-phenyl-2,9-dihydro-β-carbolin-1-one 
• 17017-72-0 1-benzyl-1H-indole-2-carboxylic acid chloride 
• 17017-71-9 1-benzyl-1H-indole-2-carboxylic acid 
• 106746-09-2 3(RS)-amino-1,1,1-trifluoro-2(RS)-hydroxy-4-methylpentane hydrochloride 
• 1026334-11-1 (9-Benzyl-1-oxo-3-phenyl-1,9-dihydro-β-carbolin-2-yl)-acetic acid 

Downstream Products

• 1026462-13-4 2-(1-Oxo-3-phenyl-1,9-dihydro-β-carbolin-2-yl)-N-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propyl)-acetamide 

Relevant academic research and scientific papers

Non-peptidic Inhibitors of Human Leukocyte Elastase. 4. Design, Synthesis, and in Vitro and in Vivo Activity of a Series of β-Carbolinone-Containing Trifluoromethyl Ketones

A novel series of human leukocyte elastase (HLE) inhibitors containing the β-carbolinone ring system are reported.The design of these trifluoromethyl ketone-based inhibitors used a combination of structural information obtained from X-ray crystallography