1027658-35-0Relevant academic research and scientific papers
Enhanced Brain Delivery of an Anti-HIV Nucleoside 2'-F-ara-ddI by Xanthine Oxidase Mediated Biotransformation
Shanmuganathan, Kirupa,Koudriakova, Tatiana,Nampalli, Satyanarayana,Du, Jinfa,Gallo, James M.,et al.
, p. 821 - 827 (1994)
In order to enhance the brain delivery of 2'-F-ara-ddI, 2'-F-ara-ddP 6 was synthesized and its in vitro and in vivo bioconversion reaction studied.For the study, a new efficient synthetic method for 2'-F-ara-ddP 6 was developed from 5-benzoyl-1,2-O-isopro
