1027981-31-2

Upstream product

• 34905-03-8 (3-(prop-2-yn-1-yloxy)phenyl)methanol 
• 124-63-0 methanesulfonyl chloride 
• 99-06-9 3-Carboxyphenol 
• 176038-82-7 3-Prop-2-ynyloxy-benzoic acid prop-2-ynyl ester 
• 620-24-6 3-Hydroxybenzyl alcohol 

Downstream Products

• 176038-89-4 5,11,17,23-tetra-tert-butyl-25,27-bis[[3-(2-propynyloxy)benzyl]oxy]calix[4]arene-26,28-diol 
• 69411-95-6 1-Bromomethyl-3-prop-2-ynyloxy-benzene 

Relevant academic research and scientific papers

Modified human four helical bundle polypeptides and their uses

Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.

MODIFIED ANIMAL ERYTHROPOIETIN POLYPEPTIDES AND THEIR USES

Modified animal erythropoietin polypeptides and uses thereof are provided.

NOVEL POLYPEPTIDE SMALL MOLECULE CONJUGATES AND THEIR USES

Novel polypeptide small molecule conjugates (PSMC) and uses thereof are provided.

Branched Acetylene-Containing Poly(Alkylene Oxides, Oxyethylated Polyols or Olefinic Alcohols)

The invention provides water-soluble compounds that include a polymer and at least one terminal azide or acetylene moiety. Also provided are highly efficient methods for the selective modification of proteins with PEG derivatives, which involves the selec

Modified FGF-21 Polypeptides and Their Uses

Modified FGF-21 polypeptides and uses thereof are provided.

BIOSYNTHETIC POLYPEPTIDE FUSION INHIBITORS

Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.

IMPROVED HUMAN INTERFERON MOLECULES AND THEIR USES

Modified human interferon polypeptides and uses thereof are provided.

Selective upper rim functionalization and lower rim bridge building with calix[4]arenes and calix[6]arenes

Selective upper rim functionalization of calix[6]arenes has been achieved by selective lower rim benzoylation at the 1,2,4,5 positions followed by AlCl3-induced removal of the tert-butyl groups of the unesterified aryl residues and introduction of various functionalities into the vacated para positions, including bromo (5), dialkylamino, (7-11) cyanomethyl (12), and (propargyloxy)methyl (13) groups. Lower rim bridge building has been achieved via oxidative coupling reactions between the aryne moieties of calix[4]arenes and calix[6]arenes in which O-benzyl groups carry one (from 23 and 24) or two (from 25) propargyloxy residues. In the calix[4]arene series both a single-spanned (32) and a double-spanned (33) double-cavity calixarene were obtained. In the calix[6]arene series only a single-spanned double cavity calixarene (36) could be characterized.