102812-65-7Relevant academic research and scientific papers
Synthesis, ir and nmr spectral correlations in some symmetrical diimines
Thirunarayanan
, p. 73 - 79 (2014)
A series of diimines have been synthesized by coupling of diamine with substituted benzaldehydes. The purities of these diimines were checked by their analytical and spectroscopic data. The spectral frequencies vCN (cm-1), NMR chemical shifts (v, ppm) of C-H and C=N of these diimines have been correlated with Hammett substituent constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral data has been studied.
Synthesis and biological evaluation of novel substituted-imidazolidine derivatives
Husain, Asif,Bhutani, Rubina,Kumar, Deepak,Shin, Dong-Soo
, p. 227 - 233 (2013/07/26)
A series of newer substituted-imidazolidine derivatives 3a-k were synthesized and assayed in vivo to investigate their anti-inflammatory, analgesic and antiulcer activity. The results of biological evaluation revealed that the three compounds, 4-[1,3-bis(4-hydroxy-3-methoxybenzyl)-2- imidazolidinyl]phenyldiethylamine (3g), 4-[1,3-bis(3-Ethoxy-4-hydroxybenzyl)-2- imidazolidinyl] phenyldiethylamine (3h) and 4-(1,3-bis(benzo[d][1,3]dioxol-5- ylmethyl)-4-methylimidazolidin-2-yl)-N,N-diethylbenzenamine (3j) were good in their anti-inflammatory and analgesic actions. Additionally these derivatives showed superior GI safety profile as compared to that of the standard drug in terms of low severity index. The results are statistically treated for its significance.
Preparation of a series of Ru(ii) complexes with N-heterocyclic carbene ligands for the catalytic transfer hydrogenation of aromatic ketones
Guerbuez, Nevin,Oezcan, Emine Oezge,Oezdemir, Ismail,Cetinkaya, Bekir,Sahin, Onur,Bueyuekguengoer, Orhan
experimental part, p. 2330 - 2339 (2012/03/22)
The reaction of [RuCl2(p-cymene]2 with Ag-N-heterocyclic carbene (NHC) complexes yields a series of [(p-cymene)Ru(NHC)] complexes (2a-f). All synthesised compounds were characterized by elemental analysis, NMR spectroscopy and the mo
Synthesis of novel tetrahydroimidazole derivatives and studies for their biological properties
Sharma, Vibha,Khan
, p. 651 - 658 (2007/10/03)
Ethylenediamine was reacted with suitable aromatic aldehydes in order to prepare their respective diSchiff bases. These compounds were then reduced to give the corresponding tetrahydrodiSchiff bases, which were low melting in nature. Finally, these derivatives were condensed with different aromatic aldehydes to give the desired tetrahydroimidazoles. The structures of all these compounds were established on the basis of spectral data. These novel tetrahydroimidazoles showed promising anti-inflammatory and analgesic activity. The compounds were also screened for their anti-bacterial property against Staphylococcus aureus and Escherichia coli.
