102875-36-5

Basic information

• Product Name: 4-(1,3-dibenzyl-2-imidazolidinyl)-N,N-dimethylaniline
• Synonyms: N-[4-(1,3-dibenzyl-2-imidazolidinyl)phenyl]-N,N-dimethylamine;4-(1,3-dibenzyl-2-imidazolidinyl)-N,N-dimethylaniline;4-(1,3-dibenzylimidazolidin-2-yl)-N,N-dimethylaniline
• CAS NO: 102875-36-5
• Molecular Formula: C25H29N3
• Molecular Weight: 371.51786
• Mol File: 102875-36-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(1,3-dibenzyl-2-imidazolidinyl)-N,N-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,3-dibenzyl-2-imidazolidinyl)-N,N-dimethylaniline(102875-36-5)
• EPA Substance Registry System: 4-(1,3-dibenzyl-2-imidazolidinyl)-N,N-dimethylaniline(102875-36-5)

Safety Data

• Hazardous Substances Data: 102875-36-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 104-71-2 N,N'-bis(benzyliden)ethylendiamine 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 140-28-3 N,N'-Dibenzylethylenediamine 

Relevant articles and documents

Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors

In order to identify novel anti-hepatitis C virus (HCV) agents we devised cell-based strategies and screened phenotypically small molecule chemical libraries with infectious HCV particles, and identified a hit compound (1) containing a hexahydropyrimidine (HHP) core. During our cell-based SAR study, we observed a conversion of HHP 1 into a linear diamine (6), which is the active component in inhibiting HCV and exhibited comparable antiviral activity to the cyclic HHP 1. In addition, we engaged into the biological characterization of HHP and demonstrated that HHP does not interfere with HCV RNA replication, but with entry and release of viral particles. Here we report the results of the preliminary SAR and mechanism of action studies with HHP.