1029009-22-0Relevant academic research and scientific papers
Heterogeneous gold(III)-catalyzed tandem cyclization of 2-alkynylbenzamides with ammonium acetate toward 1-aminoisoquinolines
Yang, Weisen,Du, Yingying,Yi, Feiyan,Cai, Mingzhong
, p. 34 - 41 (2020/06/05)
Heterogeneous tandem cyclization of 2-alkynylbenzamides with ammonium acetate is achieved in acetonitrile at 85 °C using a magnetic nanoparticles-immobilized bipy-gold(III) complex and AgSbF6 as catalysts to afford a variety of 1-aminoisoquinoline derivatives in moderate to high yields. This heterogeneous gold catalyst can be easily recovered from the reaction mixture by simply applying an external magnetic field and can be recycled at least seven times without any apparent loss of catalytic activity.
Synthesis of 1-aminoisoquinolines by gold(III)-mediated domino reactions from 2-alkynylbenzamides and ammonium acetate
Long, Yuhua,She, Zhigang,Liu, Xiaochen,Chen, Yu
, p. 2579 - 2588 (2013/04/24)
A facile synthetic route toward pharmaceutically interesting 1-aminoisoquinoline derivatives by gold(III)-mediated domino reactions is described. This synthetic protocol starts from readily available 2-alkynylbenzamides and ammonium acetate and takes plac
5, 6, or 7-Substituted - 3-(hetero) arylisoquinolinamine derivatives and therapeutic use thereof
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Page/Page column 10, (2008/12/07)
The present invention relates to 5, 6, or 7-substituted-3-(hetero)arylisoquinolinamine derivatives represented by general formula D, their pharmacologically acceptable salts thereof, and compositions containing such compounds. Methods for treating hyperproliferative disorders by administering the compounds are also included.
