1029019-93-9

Upstream product

• 1029019-98-4 tert-butyl N-(7-[methoxy(methyl)amino]-7-oxo-(E)-5-heptenyl)-N-[(R)-(1-phenylethyl)]carbamate 
• 1029019-89-3 methyl 2-((S)-1-((R)-1-phenylethyl)piperidin-2-yl)acetate 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1029020-06-1 1-[(2S)-1-[(1R)-1-phenylethyl]-2-piperidinyl]-2-propanone 
• 1029020-17-4 1-[(2S)-1-[(1R)-1-phenylethyl]-2-piperidinyl]-2-butanone 

Relevant academic research and scientific papers

Asymmetric aza-Michael addition: synthesis of (-)-allosedridine and (-)-2-epi-ethylnorlobelol

The combination of cross-metathesis and aza-Michael addition is an efficient method for generating piperidine alkaloids. Allosedridine and 2-epi-ethylnorlobelol were synthesized in six steps with ca. 25% overall yield. The aza-Michael addition is reversible for phenyl and alkyl ketones; however, the epimerization is not observed for the corresponding ester and amide.