10292-67-8 Usage
General Description
"Benzene, 1-chloro-2-cyclopropyl-" also known as Cyclopropyl chlorobenzene, is a composite chemical formed by the merging of cyclopropane (a cyclic hydrocarbon) with benzene- a colorless and flammable liquid with a sweet smell- through a chlorine atom. It is used primarily in chemical synthesis as an intermediate or starting material for more complex compounds. Some potential applications for this molecule could be in the production of certain pharmaceuticals, agrochemicals, or even plastics. As with many benzene derivatives, cyclopropyl chlorobenzene requires careful handling due to its possible damaging effects on the environment and human health.
Check Digit Verification of cas no
The CAS Registry Mumber 10292-67-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,9 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10292-67:
(7*1)+(6*0)+(5*2)+(4*9)+(3*2)+(2*6)+(1*7)=78
78 % 10 = 8
So 10292-67-8 is a valid CAS Registry Number.
10292-67-8Relevant articles and documents
Modular Functionalization of Arenes in a Triply Selective Sequence: Rapid C(sp2) and C(sp3) Coupling of C?Br, C?OTf, and C?Cl Bonds Enabled by a Single Palladium(I) Dimer
Keaveney, Sinead T.,Kundu, Gourab,Schoenebeck, Franziska
supporting information, p. 12573 - 12577 (2018/09/18)
Full control over multiple competing coupling sites would enable straightforward access to densely functionalized compound libraries. Historically, the site selection in Pd0-catalyzed functionalizations of poly(pseudo)halogenated arenes has been unpredictable, being dependent on the employed catalyst, the reaction conditions, and the substrate itself. Building on our previous report of C?Br-selective functionalization in the presence of C?OTf and C?Cl bonds, we herein complete the sequence and demonstrate the first general arylations and alkylations of C?OTf bonds (in I dimer. This allowed the realization of the first general and triply selective sequential C?C coupling (in 2D and 3D space) of C?Br followed by C?OTf and then C?Cl bonds.