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Usage

Uses

Used in Pharmaceutical Industry:
Benzene, 1-chloro-2-cyclopropylis used as a chemical intermediate for the synthesis of certain pharmaceuticals. Its unique structure allows for the creation of more complex molecules that can be utilized in the development of new drugs.
Used in Agrochemical Industry:
Benzene, 1-chloro-2-cyclopropylis used as a starting material in the production of agrochemicals. Its chemical properties make it suitable for the synthesis of compounds that can be used in the development of pesticides, herbicides, and other agricultural products.
Used in Plastics Industry:
Benzene, 1-chloro-2-cyclopropylis used as a component in the manufacturing of certain types of plastics. Its versatility in chemical reactions enables the production of plastic materials with specific properties, such as increased durability or resistance to certain conditions.

Upstream product

• 1607-29-0 bis((1-methylcyclopropyl)formyl)peroxide 
• 108-90-7 chlorobenzene 
• 873-49-4 cyclopropylbenzene 
• 95-57-8 2-monochlorophenol 
• 66107-36-6 2-chlorophenyl triflate 
• 203861-73-8 cyclopropylzinc chloride 

Downstream Products

• 129350-40-9 5-(2-chlorophenyl)-1,2-oxathiolane 2-oxide 
• 129350-40-9 5-(2-chlorophenyl)-1,2-oxathiolane 2-oxide 
• 90712-55-3 5-(2-chlorophenyl)-4,5-dihydroisoxazole 
• 57807-40-6 2-Chlor-6-nitrosopropiophenon 
• 57807-32-6 (2-chloro-6-nitrophenyl)cyclopropane 
• 57807-33-7 (2-chloro-4-nitrophenyl)cyclopropane 

Relevant academic research and scientific papers

Modular Functionalization of Arenes in a Triply Selective Sequence: Rapid C(sp2) and C(sp3) Coupling of C?Br, C?OTf, and C?Cl Bonds Enabled by a Single Palladium(I) Dimer

Full control over multiple competing coupling sites would enable straightforward access to densely functionalized compound libraries. Historically, the site selection in Pd0-catalyzed functionalizations of poly(pseudo)halogenated arenes has been unpredictable, being dependent on the employed catalyst, the reaction conditions, and the substrate itself. Building on our previous report of C?Br-selective functionalization in the presence of C?OTf and C?Cl bonds, we herein complete the sequence and demonstrate the first general arylations and alkylations of C?OTf bonds (in I dimer. This allowed the realization of the first general and triply selective sequential C?C coupling (in 2D and 3D space) of C?Br followed by C?OTf and then C?Cl bonds.

FREE RADICAL CHLORINATION AND ONE-ELECTRON OXIDATION OF ARYLCYCLOPROPANES. DESIGNER PROBES FOR CYTOCHROME P-450 HYDROXYLATION MECHANISMS

Arylcyclopropyl radicals can be formed under mild conditions (phase-transfer-catalyzed chlorination) and give rise to cyclopropyl products; in contrast one-electron oxidation of arylcyclopropanes by Mn(OAc)3 leads to fragmentation of the cyclopropane ring and the formation of acyclic products.