102932-04-7

Basic information

• Product Name: 2-bromo-6-chlorophenyl acetate
• CAS NO: 102932-04-7
• Molecular Formula: C₈H₆BrClO₂
• Molecular Weight: 249.489
• Mol File: 102932-04-7.mol

Chemical Properties

• Boiling Point: 287.7°C at 760 mmHg
• Flash Point: 127.8°C
• Density: 1.607g/cm³
• Vapor Pressure: 0.00244mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: 2-bromo-6-chlorophenyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-6-chlorophenyl acetate(102932-04-7)
• EPA Substance Registry System: 2-bromo-6-chlorophenyl acetate(102932-04-7)

Safety Data

• Hazardous Substances Data: 102932-04-7(Hazardous Substances Data)

Upstream product

• 95-57-8 2-monochlorophenol 
• 108-24-7 acetic anhydride 
• 108-95-2 phenol 

Relevant articles and documents

Bromination of phenols in bromoperoxidase-catalyzed oxidations

Phenol and ortho-substituted derivatives furnish products of selective para-bromination, if treated with sodium bromide, hydrogen peroxide, and the vanadate(V)-dependent bromoperoxidase I from the brown alga Ascophyllum nodosum. Relative rates of bromination in morpholine-4-ethane sulfonic acid (MES)-buffered aqueous tert-butanol (pH 6.2) increase by a factor 32, as the ortho-substituent in a phenol changes from F via Cl, OCH3, C(CH 3)3, and H to CH3. The polar effect in phenol bromination by the enzymatic method, according to a Hammett-correlation (ρ=-3), compares to reactivity of molecular bromine under identical conditions (ρ=-2). Hypobromous acid is not able to electrophilically substitute bromine for hydrogen at pH 6.2 in aqueous tert-butanol. The tribromide anion behaves in MES-buffered aqueous tert-butanol as electrophile (ρ～-3), showing a similar polar effect in phenol bromination as molecular bromine.