10296-76-1Relevant articles and documents
Comprehensive Synthesis of Substrates, Intermediates, and Products of the Sulfoglycolytic Embden-Meyerhoff-Parnas Pathway
Abayakoon, Palika,Epa, Ruwan,Petricevic, Marija,Bengt, Christopher,Mui, Janice W.-Y.,Van Der Peet, Phillip L.,Zhang, Yunyang,Lingford, James P.,White, Jonathan M.,Goddard-Borger, Ethan D.,Williams, Spencer J.
, p. 2901 - 2910 (2019)
Sulfoglycolysis is a metabolic pathway dedicated to the catabolism of the sulfosugar sulfoquinovose (SQ) into smaller organosulfur fragments. An estimated 10 billion tonnes of SQ fluxes through sulfoglycolysis pathways each year, making it a significant aspect of the biogeochemical sulfur cycle. Delineating the molecular details of sulfoglycolysis requires authentic samples of the various metabolites in these pathways. To this end, we have established chemical and chemoenzymatic methods for the synthesis of the key organosulfur metabolites sulfoquinovosylglycerol, SQ (also in 13C6-labeled form), sulfofructose, sulfofructose-1-phosphate, sulfolactaldehyde, and 2,3-dihydroxypropanesulfonate, as well as an improved route to the chromogenic sulfoquinovosidase substrate 4-nitrophenyl α-sulfoquinovoside.
Arsenic-containing Ribofuranosides: Isolation from Brown Kelp Ecklonia radiata and Nuclear Magnetic Resonance Spectra
Edmonds, John S.,Francesconi, Kevin A.
, p. 2375 - 2382 (2007/10/02)
2-Hydroxy-3-sulphopropyl 5-deoxy-5-(dimethylarsinoyl)-β-ribofuranoside (1a) and 2,3-dihydroxypropyl 5-deoxy-5-(dimethylarsinoyl)-β-ribofuranoside (1b) have been isolated from the brown kelp Ecklonia radiata.Extraction of a second batch of Ecklonia yielded 3-'glycerophosphoryl'-2-hydroxy-1-propane (1c) together with compound (1a).These compounds were identified chiefly by n.m.r. spectroscopy.N.m.r. data for the related (2S)-3--2-hydroxypropyl hydrogen sulphate (1d), extracted from the giant clam Tridacna maxima, are presented also.
