10299-86-2

Upstream product

• 4551-15-9 phenylthiotrimethylsilane 
• 5279-14-1 1-phenyl-1-nitropropane 
• 16336-46-2 1-phenylthio-1-phenyl-1-propene 
• 637-50-3 1-phenylpropene 
• 108-98-5 thiophenol 
• 884-09-3 phenyl thiobenzoate 
• 17336-66-2 propiophenone N-tosylhydrazone 
• 882-33-7 diphenyldisulfane 
• 93-55-0 1-phenyl-propan-1-one 
• 93-54-9 1-Phenyl-1-propanol 
• 873-49-4 cyclopropylbenzene 
• 2114-36-5 1-bromopropylbenzene 

Downstream Products

• 87413-33-0 [(1-phenylpropyl)sulfonyl]benzene 
• 95126-90-2 Phenyl-(1-phenyl-propyl)-sulfid-S-oxid 

Relevant academic research and scientific papers

Lewis Acid-catalysed Nucleophilic Displacement of the Nitro Group from Nitroalkanes

Reaction of trimethylsilyl phenyl sulphide with tertiary and benzyl nitro compounds in the presence of SnCl4 gives the corresponding sulphides.

Molybdenum (VI)-catalyzed dehydrative construction of C[sbnd]O and C[sbnd]S bonds formation via etherification and thioetherification of alcohols and thiols

An inexpensive, easily available, environmentally benign, and efficient catalyst molybdenum(VI) dioxo (acetylacetonate)2 was used for the direct oxo- and thioetherification of alcohol. This method endures selective molybdenum catalyzed dehydrative synthesis of symmetrical ethers from benzylic secondary alcohols as well as unsymmetrical ethers from the reaction of benzylic secondary alcohols with primary alcohol. Furthermore, we have been also successful in the synthesis of Aryl thioether by using alcohol and thiols.

Pd-Catalyzed Alkenyl Thioether Synthesis from Thioesters and N-Tosylhydrazones

A Pd-catalyzed alkenyl thioether synthesis was achieved using thioesters and N-tosylhydrazones as starting materials. The thioester acted as an efficient "sulfur source" for catalytic C-S bond formation using N-tosylhydrazone. This method gave Z-alkenyl thioethers with high diastereoselectivity (up to 99:1 diastereomeric ratio). This transformation displayed a wide functional group tolerance and was successfully applied to the late-stage derivatization of a pharmaceutical molecule to the corresponding alkenyl thioether.

Highly Efficient and Chemoselective Tertiary and Secondary Benzylation of Thiols Catalyzed by Indium(III) Triflate

Several examples of nucleophilic substitution reactions of compounds that have good leaving groups have been previously reported, but the direct use of simple alcohols still remains a challenge because of the poor leaving ability of the hydroxy group. Herein, an efficient and highly chemoselective method for the S-benzylation of a wide range of aromatic and aliphatic thiols has been accomplished in the presence of catalytic amounts (0.1–0.2 mol-%) of indium(III) triflate. Our approach is atom efficient (water is the only byproduct) and suitable to obtain the corresponding unsymmetrical thioethers in excellent yields (up to 99 %). The low loading of catalyst that are needed to obtain extraordinarily high chemoselectivities and the generality of the reaction make this approach unique.

Iron-catalysed Markovnikov hydrothiolation of styrenes

The bis(triflimide)iron(III) salt catalyzes the hydrothiolation of styrenes in a Markovnikov fashion with good selectivities and high yields. After isolation, different benzylic thioethers are obtained. This iron(III) catalyst is unique in terms of regioselectivity and represents a sustainable and economic alternative to those processes based on stoichiometric reagents. Copyright

REACTION OF ARYLCYCLOPROPANES WITH THIOPHENOLS UNDER ACID CATALYSIS CONDITIONS

A study was carried out on the reaction of substituted phenylcyclopropanes with equimolar amounts of thiophenols in trifluoroacetic acid.Phenylcyclopropanes resistant to the action of trifluoroacetic acid undergo opening of the small ring in the presence

TITANIUM TETRACHLORIDE PROMOTED REDUCTION OF ALKENYL SULFIDES USING TRIETHYLSILANE AS A REDCING AGENT

Alkenyl sulfides were reduced to the corresponding alkyl sulfides with triethylsilane in the presence of titanium tetrachloride in good yields.The reduction proceeds via -phenylthio-alkyltitanium intermediate.