102996-95-2

Basic information

• Product Name: 4-methyl-N-(2-(thiophen-2-yl)ethyl)benzenesulfonamide
• Synonyms: 4-methyl-N-(2-(thiophen-2-yl)ethyl)benzenesulfonamide
• CAS NO: 102996-95-2
• Molecular Weight: 281.4
• Mol File: 102996-95-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(2-(thiophen-2-yl)ethyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(2-(thiophen-2-yl)ethyl)benzenesulfonamide(102996-95-2)
• EPA Substance Registry System: 4-methyl-N-(2-(thiophen-2-yl)ethyl)benzenesulfonamide(102996-95-2)

Safety Data

• Hazardous Substances Data: 102996-95-2(Hazardous Substances Data)

Upstream product

• 30433-91-1 [2-(2-thyenyl)ethyl]amine 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 98-59-9 p-toluenesulfonyl chloride 
• 188290-36-0 thiophene 
• 3634-89-7 N-(p-toluenesulfonyl)aziridine 

Downstream Products

• 30433-91-1 [2-(2-thyenyl)ethyl]amine 
• 102996-96-3 ethyl N,N-<2-(2-thienyl)ethyl>tosylglycinate 
• 102997-16-0 6-(2-chlorobenzyl)-5,6,7,8-tetrahydro-4H-thieno<2,3-d>azepine 
• 102997-01-3 5,6,7,8-tetrahydro-4H-thieno<2,3-d>azepine 
• 102996-97-4 N,N-<2-(2-thienyl)ethyl>tosylglycine 
• 102996-99-6 4-hydroxy-6-tosyl-5,6,7,8-tetrahydro-4H-thieno<2,3-d>azepine 
• 102996-98-5 6-tosyl-5,6,7,8-tetrahydrothieno<2,3-d>azepin-4-one 
• 102997-02-4 6-tosyl-7,8-dihydro-6H-thieno<2,3-d>azepine 

Relevant articles and documents

Direct Synthesis of α-Amino Nitriles from Sulfonamides via Base-Mediated C-H Cyanation

Herein, we disclose a transition-metal-free reaction system that enables α-cyanation of sulfonamides through C-H bond cleavage for the preparation of α-amino nitriles, including difficult-to-access all-alkyl α-tertiary scaffolds. More than 50 substrate examples prove a wide functional group tolerance. Additionally, its synthetic practicality is highlighted by gram-scalability and the late-stage modification of natural compounds. Mechanistic experiments suggest that this process involves in situ formation of an imine intermediate via base-promoted elimination of HF.

Enantioselective Synthesis of trans-Vicinal Diamines via Rhodium-Catalyzed [2+2] Cycloaddition of Allenamides

An efficient protocol for the enantioselective Rh-catalyzed intermolecular head-to-head [2+2] cycloaddition of allenamides was developed. A variety of enantio-enriched cyclobutane-1,2-diamine derivatives were achieved in good yields with good to excellent enantioselectivities. (Figure presented.).

New synthesis of 5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine

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