103-62-8

Basic information

• Product Name: p-Hydroxyphenyl-n-butylamine
• Synonyms: 4-(BUTYLAMINO)PHENOL;N-BUTYL-P-AMINOPHENOL;N-BUTYL-PARA-AMINOPHENOL;p-(Butylamino)phenol;p-BAP
• CAS NO: 103-62-8
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• EINECS: 203-129-2
• Mol File: 103-62-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 70-71 °C
• Boiling Point: 293.09°C (rough estimate)
• Flash Point: 128.9°C
• Appearance: /
• Density: 1.0203 (rough estimate)
• Vapor Pressure: 0.000537mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• PKA: 11.03±0.26(Predicted)
• CAS DataBase Reference: p-Hydroxyphenyl-n-butylamine(CAS DataBase Reference)
• NIST Chemistry Reference: p-Hydroxyphenyl-n-butylamine(103-62-8)
• EPA Substance Registry System: p-Hydroxyphenyl-n-butylamine(103-62-8)

Safety Data

• Hazardous Substances Data: 103-62-8(Hazardous Substances Data)

Usage

General Description

p-Hydroxyphenyl-n-butylamine, also known as 4-Hydroxyphenylbutylamine or p-Hydroxy-N-butylphenethylamine, is an organic compound that consists of a phenyl ring with a hydroxyl group (OH) and a butylamine side chain (C4H9NH2) attached to the para (p-) position of the phenyl ring.

InChI:InChI=1/C10H15NO/c1-2-3-8-11-9-4-6-10(12)7-5-9/h4-7,11-12H,2-3,8H2,1H3

Upstream product

• 123-30-8 4-amino-phenol 
• 123-72-8 butyraldehyde 
• 109-73-9 N-butylamine 
• 100-02-7 4-nitro-phenol 

Downstream Products

• 23838-65-5 4-(Butyl-methyl-amino)-phenol 
• 16222-29-0 4-N,N-dibutylaminophenol 

Relevant articles and documents

Enhancement of antioxidant activity of p-alkylaminophenols by alkyl chain elongation

The initial finding that the p-methylaminophenol (6) exhibited antioxidant activity led us to investigate whether the length of alkyl chains linked to the aminophenol residue might affect antioxidative activity. Therefore, we synthesized p-butylaminophenol (5), p-hexylaminophenol (4), p-octylaminophenol (3), and p-methoxybenzylaminophenol (7). All p-alkylaminophenols quenched α,α-diphenyl-β-picrylhydrazyl (DPPH) radicals, with 7 being the most potent DPPH radical scavenger. Lipid peroxidation by rat liver microsomes was reduced by p-alkylaminophenols in dose- and aminophenol alkyl chain length-dependent fashion (3>4>5>6), with 3 being the most potent lipid peroxidation inhibitor, at approximately 350-fold higher potency than 6. These results indicate that elongation of alkyl chains in p-alkylaminophenols may increase antioxidative activity, and that p-alkylaminophenols may potentially be useful in the development of antioxidants.

One-pot reductive mono-N-alkylation of aniline and nitroarene derivatives using aldehydes

(Chemical Equation Presented) One-pot reductive mono-N-alkylation of aniline and nitroarene derivatives using various aldehydes by Pd/C catalyst in aqueous 2-propanol solvent with ammonium formate as in situ hydrogen donor is illustrated. The reaction proceeded smoothly and selectively with excellent yield at room temperature. Our protocol presents a facile, economical, and environmentally benign alternative for reductive amination.

Corrosion inhibiting composition

A composition, in contact with a corrodable metal surface, which composition comprises: (a) an aqueous-based or oil-based system; and (b) as inhibitor for protecting the metal surface against corrosion, at least one compound having the formula I: STR1 as well as salts or partial esters thereof wherein: n is 0 or an integer ranging from 1 to 20, R is a straight or branched chain C4 -C30 alkyl group, optionally interrupted by one, two or three oxygen atoms or substituted by one, two or three hydroxy groups, a C5 -C12 cycloalkyl group, a C6 -C10 aryl group optionally substituted by one, two or three C1 -C12 alkyl groups, or a C7 -C13 aralkyl group which is optionally substituted by a hydroxyl group; R1 is H or a straight- or branched chain C1 -C4 alkyl group; R2 is H, a straight or branched chain C1 -C4 alkyl group or CO2 H; R3 is H, a straight or branched chain C1 -C4 alkyl group, --CH2 CO2 H or --CH2 CH2 CO2 H; R4 is H, a straight or branched chain C1 -C4 alkyl group or CO2 H; R5 is H, a straight or branched chain C1 -C4 alkyl group, CH2 CO2 H or CH2 CH2 CO2 H; provided that at least one group R4 must be CO2 H, with the provisio, that compositions comprising an oil-based system and a compound having the formula STR2 wherein R, R1 and R2 are hydrogen or alkyl radicals, having a total from 10 to 38 C-atoms, are excluded.