103123-64-4

Upstream product

• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 
• 27829-72-7 ethyl (E)-hex-2-enoate 
• 222425-48-1 (3R,7R)-ethyl N-(α-methylbenzyl benzyl)-3-aminohexanoate 

Downstream Products

• 884318-87-0 (2S,3R)-ethyl 3-(N-((R)-1-phenylethyl)amino)-2-(phenylselanyl)hexanoate 
• 884318-88-1 (2R,3R)-ethyl 3-(N-((R)-1-phenylethyl)amino)-2-(phenylselanyl)hexanoate 

Relevant academic research and scientific papers

Stereoselective reduction of enantiopure β-enamino esters by hydride: A convenient synthesis of both enantiopure β-amino esters

The reduction of enantiopure β-enamino esters 1 with sodium triacetoxyborohydride in acetic acid is described. This occurs with good diastereo- and enantioselectivity to yield β-amino esters 2 and 3 (after hydrogenolysis of the N-chiral group). A model is

Diastereoselective synthesis of aziridine esters via amino selanyl esters

A synthesis of aziridine esters based on the cyclisation of amino selanyl esters induced by the selanyl group activation was developed with either the Meerwein salt or NBS. Two asymmetric approaches are proposed: the diastereoselective reductions of α-sel

Diastereo and Enantioselective Entry to β-Amino Esters by Hydride Reduction of Homochiral β-Enamino Esters.

The reduction of homochiral β-enamino esters 1 with sodium triacetoxyborohydride, which occurs with good diastereo- and enantioselectivity in the β-amino esters 2, is described.The procedure allows a straightforward preparation of compounds with known bio